One of the first clinical symptoms III long-term diabetic patients is nephropathy with the subsquent micro albuminuria. In this study 24 urine samples were collected from 63 long-term (more than 10 years) diabetic patients attending Zanjan diabetic clinic. Sampling was repeated three times over 6 months with two-month intervals to confirm the observation. Meanwhile a questionnaire was prepared for each patient with respect to his/her identification and background. Bromo phenol blue method was used for albuminuria measurement, which is a simple, rapid and low-cost method.The results revealed that an outstanding number of patients (60.4%) had unstable microalbuminuria (30 to 300 mg in 24h urine) while 39.6% of them had stable microlbuminuria (2 out of 3 stages of 24 urine samples in 6 month period included more than 300 mg albumin). Using k square method, it was found that there was no significant difference between IDDM and NIDDM patients whose urine samples included over 300 mg albumin in 2 stages out of three. There were significant differences (P<0.01) between patients with over and under 15 years of diabetes who had at least 2 stages out of three of 24h urine samples over 300 mg albumin. This presents that patients with 15 years of diabetes are more nephropathic. There was no significant difference between males and females in albuminuria stability. This estimate might be of value in predicting nephropathy prevalence in Zanjan city.
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مقاله پژوهشی |
دریافت: 1387/8/21 | پذیرش: 1380/3/25 | انتشار: 1380/3/25