دوره 26، شماره 116 - ( 5-1397 )                   جلد 26 شماره 116 صفحات 47-35 | برگشت به فهرست نسخه ها

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Raisi Z, Faramarzi M, Banitalebi E, Samieyan M. The Effect of 12 Weeks Combined (Strength, Endurance, Pilates, PNF) Exercise Training on Fibrin D-Dimer (FDD) and Interleukin-6 Levels in Female Multiple Sclerosis Patients with Different Levels of Disability. J Adv Med Biomed Res 2018; 26 (116) :35-47
URL: http://journal.zums.ac.ir/article-1-5096-fa.html
رئیسی زهرا، فرامرزی محمد، بنی طالبی ابراهیم، سمیعیان معصومه. تاثیر دوازده هفته تمرینات ورزشی ترکیبی (قدرتی، استقامتی، پیلاتس و PNF) بر سطوح فیبرین دی دایمر (FDD) و اینترلوکین-6 در بیماران زن مبتلا به مولتیپل اسکلروزیس با درجات مختلف ناتوانی. Journal of Advances in Medical and Biomedical Research. 1397; 26 (116) :35-47

URL: http://journal.zums.ac.ir/article-1-5096-fa.html


1- کارشناس ارشد فیزیولوژی ورزشی، دانشگاه شهرکرد، شهرکرد
2- دکترای تخصصی فیزیولوژی ورزشی، دانشیار گروه تربیت بدنی و علوم ورزشی، دانشگاه شهرکرد، شهرکرد
3- دکترای تخصصی فیزیولوژی ورزشی، استادیار گروه تربیت بدنی و علوم ورزشی دانشگاه شهرکرد، شهرکرد
4- کارشناس ارشد فیزیولوژی ورزشی دانشگاه شهرکرد، شهرکرد
چکیده:   (167325 مشاهده)

Background and Objective: Multiple Sclerosis (MS) is a neurological disorder that can restrict individual's ability to carry on their activities. The aim of this study was to examine the effects of combined exercise training on serum Fibrin D-Dimer (FDD) and interleukin-6 in female multiple sclerosis patients with different levels of disability.
Materials and Methods: 96 female patients with MS were selected and were divided into three groups based on their physical disability scale scores (EDSS): low disability (n=44), moderate disability (n=26) and severe disability (n=26). Afterwards, participants of each group were randomly divided into an experimental and a control group. Participants performed 12 weeks combined strength, endurance, Pilates and PNF training, three sessions per week, 45 to 60 minute for each session. Dependent and independent t-test was used to compare means between and within groups, respectively.
Results: The results showed a significant decrease in fibrin D-dimer (p= 0.001) and interleukin-6 (p= 0.001) in the low disability group and interleukin-6 (p=0.004) in the severe disability group.
Conclusion: It appears that performing combined exercise training results in a decrease in fibrin D-dimer, interleukin-6 and inflammation in low disability MS patients. Thus, these exercises are recommended as a complementary therapy alongside drug treatments for M.S patients.

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نوع مطالعه: مقاله پژوهشی |
دریافت: 1396/12/14 | پذیرش: 1396/12/14 | انتشار: 1396/12/14

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