From the first reported case of Coronavirus disease 2019 (COVID-19) on December 30, 2019 in Wuhan, China, the number of confirmed cases of the disease has been increased continuously and exponentially up to now. The event has emerged as a clear threat to global health such that the World Health Organization (WHO) officially declared the outbreak of the disease a pandemic on March 11, 2020. The disease has infected approximately 195,000 people and killed about 7,700 in the Eastern Mediterranean Region. As COVID-19 is spreading globally, its economic consequences also mounting across all countries. This perspective research designed to examine briefly the economic consequences of COVID-19 on the Middle East and North Africa (MENA) Region Countries.