دوره 31، شماره 144 - ( 10-1401 )                   جلد 31 شماره 144 صفحات 24-14 | برگشت به فهرست نسخه ها


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Nasehi Z, Shahaboddin M E, Jafarnejad S. The Influence of Securigera securidaca on Diabetes Management in Animal Models: A Systematic Review. J Adv Med Biomed Res 2023; 31 (144) :14-24
URL: http://journal.zums.ac.ir/article-1-6789-fa.html
The Influence of Securigera securidaca on Diabetes Management in Animal Models: A Systematic Review. Journal of Advances in Medical and Biomedical Research. 1401; 31 (144) :14-24

URL: http://journal.zums.ac.ir/article-1-6789-fa.html


چکیده:   (11392 مشاهده)

Background and Objective: It has been reported that allopathic drugs do not have significant effects on diabetes treatment. In contemporary literature, much attention has been given to the potential use of traditional medicines, including medicinal plants, in the treatment of metabolic abnormalities. Indeed, the effect of Securigera securidaca, as a medicinal agent, in alleviating the complications of diabetes has received marked attention, particularly in animal models. The aim of this review is to clarify the S.securidaca therapeutic effects in diabetes mellitus treatment based on animal research.
Materials and Methods: PubMed, Google Scholar, and the Web of Science were searched, from inception to January 2020 to investigate the effects of S.securidaca on diabetes in animal models. Each article was critically rewired for its methodological quality using the CAMARADE tool.
Results: Thirteen articles were reviewed and some positive effects of S.securidaca were observed in alloxan and Streptozotocin-induced diabetic animals. With a closer look at the mechanisms, S.securidaca is comparable with current antidiabetic drugs. The results of animal trials indicated hypoglycemic effects of S.securidaca in animal models.
Conclusion: Remedies like S.securidaca could count as a treatment option for diabetic patients, alongside current antidiabetic medications, yet with fewer side-effects.

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نوع مطالعه: مقاله مروری | موضوع مقاله: Medical Biology
دریافت: 1400/8/21 | پذیرش: 1401/7/26 | انتشار: 1401/9/21

فهرست منابع
1. Pang GM, Li FX, Yan Y, et al. Herbal medicine in the treatment of patients with type 2 diabetes mellitus. Chinese Med J. 2019;132(01):78-85. [DOI:10.1097/CM9.0000000000000006] [PMID] [PMCID]
2. Zimmet P, Alberti K, Shaw J. Global and societal implications of the diabetes epidemic. Nature. 2001;414(6865):782-7. [DOI:10.1038/414782a] [PMID]
3. Kasole R, Martin HD, Kimiywe J. Traditional medicine and its role in the management of diabetes mellitus:"patients' and herbalists' perspectives". Evid Base Complement Alternat Med. 2019;2019. [DOI:10.1155/2019/2835691] [PMID] [PMCID]
4. Nahas R, Moher M. Complementary and alternative medicine for the treatment of type 2 diabetes. Can Fam Physician. 2009;55(6):591-6.
5. Moradi B, Abbaszadeh S, Shahsavari S, Alizadeh M, Beyranvand F. The most useful medicinal herbs to treat diabetes. Biomed Res Ther. 2018;5(8):2538-51. [DOI:10.15419/bmrat.v5i8.463]
6. Ekor M. The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety. Front Pharmacol. 2014;4:177. [DOI:10.3389/fphar.2013.00177] [PMID] [PMCID]
7. Valdez-Solana MA, Mejia-Garcia VY, Tellez-Valencia A, et al. Nutritional content and elemental and phytochemical analyses of Moringa oleifera grown in Mexico. J Chemist. 2015;2015(6):1-9 [DOI:10.1155/2015/860381]
8. Vanani AR, Mahdavinia M, Kalantari H, Khoshnood S, Shirani M. Antifungal effect of the effect of Securigera securidaca L. vaginal gel on Candida species. Curr Med Mycol. 2019;5(3):31.
9. Nik AB, Vazifedoost M, Didar Z, Hajirostamloo B. The antioxidant and physicochemical properties of microencapsulated bioactive compounds in Securigera securidaca (L.) seed extract by co-crystallization. Food Qual Safety. 2019;3(4):243-50. [DOI:10.1093/fqsafe/fyz022]
10. Rajaei Z, Moradi R, Ghorbani A, Saghebi A. Antihyperglycemic and antihyperlipidemic effects of hydroalcoholic extract of Securigera securidaca seeds in streptozotocin-induced diabetic rats. Adv Biomed Res. 2015;4:33 [DOI:10.4103/2277-9175.150427] [PMID] [PMCID]
11. Amin G. Popular medicinal plants of Iran. Sci Res.1991:40-7.
12. Behbahani M, Shanehsazzadeh M, Shokoohinia Y, Soltani M. Evaluation of anti-herpetic activity of methanol seed extract and fractions of Securigera securidaca in vitro. J Antivir Antiretrovir. 2013;5(4):72-6.
13. Al-Hachim GM, Maki B. Effect of Securigera securidaca on electroshock seizure threshold in mice. Psychol Rep. 1969;24(2):551-3. [DOI:10.2466/pr0.1969.24.2.551] [PMID]
14. Mard S, Bahari Z, Eshaghi N, Farbood Y. Antiulcerogenic effect of Securigera securidaca L. seed extract on various experimental gastric ulcer models in rats. Pakistan J Biol Sci. 2008;11(23):2619. [DOI:10.3923/pjbs.2008.2619.2623] [PMID]
15. Jamshidzadeh A, Pasdaran A, Heidari R. Pharmacognostic and anti-inflammatory properties of Securigera securidaca seeds and seed oil. Res J Pharmacog. 2018;5(3):31-9.
16. Ancolio C, Azas N, Mahiou V, et al. Antimalarial activity of extracts and alkaloids isolated from six plants used in traditional medicine in Mali and Sao Tome. Phytother Res. 2002;16(7):646-9. [DOI:10.1002/ptr.1025] [PMID]
17. Camarades. Collaborative approach to meta-analysis and review of animal data from Experimental Studies. 2014.
18. Ahmadi A, Khalili M, Margedari S, Nahri-Niknafs B. Antidiabetic and antilipidemic effects of some polar and nonpolar extracts of securigera securidaca flowers. Pharmaceut Chem J. 2016;49(11):753-9. [DOI:10.1007/s11094-016-1365-6]
19. Ahmadi A, Khalili M, Margedari S, Nahri-Niknafs B. The effects of solvent polarity on hypoglycemic and hypolipidemic activities of Securigera securidaca (L.) seeds. Drug Res. 2016;66(03):130-5. [DOI:10.1055/s-0035-1555773] [PMID]
20. Alizadeh-Fanalou S, Babaei M, Hosseini A, et al. Effects of Securigera Securidaca seed extract in combination with glibenclamide on antioxidant capacity, fibroblast growth factor 21 and insulin resistance in hyperglycemic rats. J Ethnopharmacol. 2020;248:112331. [DOI:10.1016/j.jep.2019.112331] [PMID]
21. Hosseinzadeh H, Ramezani M, Danaei A. Antihyperglycaemic effect and acute toxicity of Securigera Securidaca L. seed extracts in mice. Phytother Res. 2002;16(8):745-7. [DOI:10.1002/ptr.1020] [PMID]
22. Ibrahim RM, El-Halawany AM, Saleh DO, Naggar EMBE, El-Shabrawy AE-RO, El-Hawary SS. HPLC-DAD-MS/MS profiling of phenolics from Securigera securidaca flowers and its anti-hyperglycemic and anti-hyperlipidemic activities. Revista Brasileira de Farmacognosia. 2015;25(2):134-41. [DOI:10.1016/j.bjp.2015.02.008]
23. Mahdi P, Mohammad ES, Ali-Akbar M, Karim P. To study the effects of Securigera securidaca (L.) seed against alloxan-induced hyperglycemia. J Med Plant Res. 2011;5(14):3188-91.
24. Minaiyana M, Moattar F, Vali A. Effect of Securigera securidaca seeds on blood glucose level of normal and diabetic rats. Iran J Pharmaceut Sci. 2006;2(3):151-6.
25. Porchezhian E, Ansari S. Effect of Securigera securidaca on blood glucose levels of normal and alloxan-induced diabetic rats. Pharmaceut Biol. 2001;39(1):62-4. [DOI:10.1076/phbi.39.1.62.5949]
26. Tofighi Z, Moradi-Afrapoli F, Ebrahimi SN, et al. Securigenin glycosides as hypoglycemic principles of Securigera securidaca seeds. J Nat Med. 2017;71(1):272-80. [DOI:10.1007/s11418-016-1060-7] [PMID]
27. Gheitasi I, Nikbakht M, Sadeghi H, Sabzali V, Sabzali S, Shahrani M. The hypoglycemic effects of a hydro-alcoholic extract from Securigera securidaca seeds on induced diabetic in male rats. Journal of Shahrekord Uuniversity of Medical Sciences. 2007;8.
28. Tofighi Z, Sabzevari O, REZAEI TZ, Yassa N. Investigation of securigera securidaca seeds extract and different fractions on serum glucose, blood factors and liver morphology in diabetic animals. 2016.
29. Zahedi-Asl S, Marahel H, Zaree B. Study on the effects of chloroformic extract of Securigera Securidaca on serum glucose level and liver glycogen content of mice. Journal of Kerman University of medical sciences. 2005;11(1):32-8.
30. Dabe NE, Kefale AT. Antidiabetic effects of artemisia species: a systematic review. Ancient science of life. 2017;36(4):175. [DOI:10.4103/asl.ASL_87_17] [PMID] [PMCID]

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