یکشنبه 14 بهمن 1403
[Archive]
دوره 31، شماره 147 - ( 5-1402 )
جلد 31 شماره 147 صفحات 341-330 |
برگشت به فهرست نسخه ها
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Ebrahimi-Nejad F, Oraee-Yazdani S, Vahedi M, Peyravi Dehsorkhi M, Hosseinzadeh S. Relationship between CT-Scan Findings and Longitudinal Blood Markers with the Occurrence of Death among Comatose Patients Due to Traumatic Brain Injury: Retrospective Longitudinal Study. J Adv Med Biomed Res 2023; 31 (147) :330-341
URL: http://journal.zums.ac.ir/article-1-6837-fa.html
URL: http://journal.zums.ac.ir/article-1-6837-fa.html
Relationship between CT-Scan Findings and Longitudinal Blood Markers with the Occurrence of Death among Comatose Patients Due to Traumatic Brain Injury: Retrospective Longitudinal Study. Journal of Advances in Medical and Biomedical Research. 1402; 31 (147) :330-341
چکیده: (1361 مشاهده)
Background and Objective: Blood markers and CT-scan results can be useful to the prognosis outcome of traumatic brain injury (TBI). This study aims to evaluate and compare markers and CT-scans during hospitalization regarding death and recovery as the outcomes.
Materials and Methods: This longitudinal-observational retrospective study was performed on 133 patients with comatose caused by head trauma from admission to death/discharge in Shohada-E- Tajrish Hospital in Tehran during 2018-2020. The follow-up period lasted 15 days. The patients’ demographic and CT-scans were measured on admission. Blood markers were measured daily. Vital signs and GCS were collected every six hours. These variables were compared in survivor and non-survivor groups.
Results: Death occurred for 78 patients (58.64%). Tachycardia (OR=60.1, P=0.003), SDH (OR=39.3, P<0.001), ICH (OR=9.91, P<0.001), SAH (OR=13.6, P<0.001) had a significant relationship to death on multivariate logistic regression. The mean TT, PT, INR, GCS, PR, and systolic and diastolic blood pressure at the beginning of hospitalization were significantly different in the surviving and non-surviving groups. GCS, Cr, BUN, PTT, PT, INR, FBS, and PH had separate lines with spacing without overlap in the two groups in the graphs during hospitalization.
Conclusion: Based on the results, the factors such as age, tachycardia, and some CT-scan findings (SAH, ICH, and SDH), as well as high coagulation profile (INR, PTT) and low GCS on admission, were important variables to the prognosis of TBI patients. During hospitalization, high values of BUN, PR, Cr, FBS, PT, and INR and low values of GCS, RR, and PH were associated with a worthwhile outcome. In addition, high changes in BUN, GCS, RR, PR, and BP during hospitalization should be considered a worthwhile prognosis.
نوع مطالعه: مقاله پژوهشی |
موضوع مقاله:
Epidemiologic studies
دریافت: 1401/5/13 | پذیرش: 1401/10/6 | انتشار: 1402/7/5
دریافت: 1401/5/13 | پذیرش: 1401/10/6 | انتشار: 1402/7/5
فهرست منابع
1. Reza A, Riahi E, Daneshi A, Golchini E. The incidence of traumatic brain injury in Tehran, Iran. Brain Inj. 2018;32(4):487-92. [DOI:10.1080/02699052.2018.1429658] [PMID]
2. Kasmaei VM, Asadi P, Zohrevandi B, Raouf MT. An epidemiologic study of traumatic brain injuries in emergency department. Emergency. 2015;3(4):141.
3. Ziaeirad M, Alimohammadi N, Irajpour A, Aminmansour B. Association between outcome of severe traumatic brain injury and demographic, clinical, injury-related variables of patients. Iran J Nurs Midwif Res. 2018;23(3):211 [DOI:10.4103/ijnmr.IJNMR_65_17] [PMID] [PMCID]
4. Ţolescu RŞ, ZorilĂ MV, ZĂvoi RE, et al. Correlations between the Glasgow score and the survival period in patients with severe traumatic brain injury. Curr Health Sci J. 2020;46(4):412.
5. Brooks JC, Shavelle RM, Strauss DJ, Hammond FM, Harrison-Felix CL. Long-term survival after traumatic brain injury part II: Life expectancy. Arch Phys Med Rehabil. 2015;96(6):1000-5. [DOI:10.1016/j.apmr.2015.02.003] [PMID]
6. Steppacher I, Kaps M, Kissler J. Against the odds: a case study of recovery from coma after devastating prognosis. Ann Clin Transl Neurol. 2016;3(1):61-5. [DOI:10.1002/acn3.269] [PMID] [PMCID]
7. Visser K, Koggel M, Blaauw J, van der Horn HJ, Jacobs B, van der Naalt J. Blood-based biomarkers of inflammation in mild traumatic brain injury: A systematic review. Neurosci & Biobehav Rev. 2022;132:154-68. [DOI:10.1016/j.neubiorev.2021.11.036] [PMID]
8. Kim JJ, Gean AD. Imaging for the diagnosis and management of traumatic brain injury. Neurotherapeutics. 2011;8(1):39-53. [DOI:10.1007/s13311-010-0003-3] [PMID] [PMCID]
9. Mushkudiani NA, Engel DC, Steyerberg EW, et al. Prognostic value of demographic characteristics in traumatic brain injury: results from the IMPACT study. J Neurotrauma. 2007;24(2):259-69. [DOI:10.1089/neu.2006.0028] [PMID]
10. Ghaffarzad A, Pouraghaei M, Parsian Z, Ghilani N, Cicek M, Khorami FS. Diagnostic and predictive value of white blood cell count, erythrocyte sedimentation rate, and coagulation tests in patients with blunt head trauma. J Res Clin Med. 2020;8(1):3. [DOI:10.34172/jrcm.2020.003]
11. McNett M. A review of the predictive ability of Glasgow Coma Scale scores in head-injured patients. J Neurosci Nurs. 2007;39(2):68-75. [DOI:10.1097/01376517-200704000-00002] [PMID]
12. Gardner RC, Dams-O'Connor K, Morrissey MR, Manley GT. Geriatric traumatic brain injury: Epidemiology, outcomes, knowledge gaps, and future directions. J Neurotrauma. 2018;35(7):889-906. [DOI:10.1089/neu.2017.5371] [PMID] [PMCID]
13. Stocchetti N, Paterno R, Citerio G, Beretta L, Colombo A. Traumatic brain injury in an aging population. J Neurotrauma. 2012;29(6):1119-25. [DOI:10.1089/neu.2011.1995] [PMID]
14. Hukkelhoven CW, Steyerberg EW, Rampen AJ, et al. Patient age and outcome following severe traumatic brain injury: an analysis of 5600 patients. J Neurosurg. 2003;99(4):666-73. [DOI:10.3171/jns.2003.99.4.0666] [PMID]
15. Liu C, Xie J, Xiao X, et al. Clinical predictors of prognosis in patients with traumatic brain injury combined with extracranial trauma. Int J Med Sci. 2021;18(7):1639-47. [DOI:10.7150/ijms.54913] [PMID] [PMCID]
16. Maggiore U, Picetti E, Antonucci E, et al. The relation between the incidence of hypernatremia and mortality in patients with severe traumatic brain injury. Crit Care. 2009;13(4):1-9. [DOI:10.1186/cc7953] [PMID] [PMCID]
17. Fitzmaurice GM, Laird NM, Ware JH. Applied longitudinal analysis: John Wiley & Sons; 2012. [DOI:10.1002/9781119513469]
18. Harrois A, Anstey JR, van der Jagt M, et al. Variability in serum sodium concentration and prognostic significance in severe traumatic brain injury: A multicenter observational study. Neurocrit Care. 2021;34(3):899-907. [DOI:10.1007/s12028-020-01118-8] [PMID]
19. Ssebakumba MK, Lule H, Olweny F, Mabweijano J, Kiryabwire J. Thirty-day clinical outcome of traumatic brain injury patients with acute extradural and subdural hematoma: a cohort study at Mulago National Referral Hospital, Uganda. Egypt J Neurosurg. 2020;35(1):1-12. [DOI:10.1186/s41984-020-0073-4]
20. Huseyin Fatih G, Dolanbay T, Simsek AT, Aras M. Evaluation of blood urea, creatinine, and glucose levels as biochemical indicators of the type and severity of traumatic brain injury. Turk Neurosurg. 2021;31(3):333-8.
21. Van Beek JG, Mushkudiani NA, Steyerberg EW, et al. Prognostic value of admission laboratory parameters in traumatic brain injury: results from the IMPACT study. J Neurotrauma. 2007;24(2):315-28. [DOI:10.1089/neu.2006.0034] [PMID]
22. de Oliveira Manoel AL, Neto AC, Veigas PV, Rizoli S. Traumatic brain injury associated coagulopathy. Neurocrit Care. 2015;22(1):34-44. [DOI:10.1007/s12028-014-0026-4] [PMID]
23. Rovlias A, Kotsou S. The blood leukocyte count and its prognostic significance in severe head injury. Surg Neurol. 2001;55(4):190-6. [DOI:10.1016/S0090-3019(01)00414-1] [PMID]
24. Nelson DW, Rudehill A, MacCallum RM, et al. Multivariate outcome prediction in traumatic brain injury with focus on laboratory values. J Neurotrauma. 2012;29(17):2613-24. [DOI:10.1089/neu.2012.2468] [PMID]
25. Morgan E, Bankole O, Kanu O, Ojo O, Poluyi E. Comparison of the predictive strength of total white blood cell count within 24 hours on outcome of traumatic brain injury with Glasgow Coma Score and pupillary reactivity. J Clin Case Rep Trials. 2018;1:10-3. [DOI:10.33962/roneuro-2019-010]
26. Dolmans RG, Hulsbergen AF, Gormley WB, Broekman ML. Routine blood tests for severe traumatic brain injury: can they predict outcomes? World Neurosurg. 2020;136:e60-e7. [DOI:10.1016/j.wneu.2019.10.086] [PMID]
27. Gurkanlar D, Lakadamyali H, Ergun T, Yilmaz C, Yucel E, Altinors N. Predictive value of leucocytosis in head trauma. Turk Neurosurg. 2009;19(3):211-5.
28. Yuan Q, Yu J, Wu X, et al. Prognostic value of coagulation tests for in-hospital mortality in patients with traumatic brain injury. Scand J Trauma Resusc Emerg Med. 2018;26(1):3. [DOI:10.1186/s13049-017-0471-0] [PMID] [PMCID]
29. Wu X, Lu X, Lu X, et al. Prevalence of severe hypokalaemia in patients with traumatic brain injury. Injury. 2015;46(1):35-41. [DOI:10.1016/j.injury.2014.08.002] [PMID]
30. Beal AL, Scheltema KE, Beilman GJ, Deuser WE. Hypokalemia following trauma. Shock. 2002;18(2):107-10. [DOI:10.1097/00024382-200208000-00002] [PMID]
31. Shibahashi K, Sugiyama K, Okura Y, Tomio J, Hoda H, Hamabe Y. Defining hypotension in patients with severe traumatic brain injury. World Neurosurg. 2018;120:e667-e74. [DOI:10.1016/j.wneu.2018.08.142] [PMID]
32. Moore L, Lavoie A, Camden S, et al. Statistical validation of the Glasgow Coma Score. J Trauma. 2006;60(6):1238-43. [DOI:10.1097/01.ta.0000195593.60245.80] [PMID]
33. Kusuma GFP, Maliawan S, Mahadewa TGB, Senapathi TGA, Lestari AAW, Muliarta IM. Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio correlations with C-reactive protein and erythrocyte sedimentation rate in traumatic brain injury. Open Access Macedonian J Med Sci. 2020;8(B):1185-92. [DOI:10.3889/oamjms.2020.5544]
34. Scotter J, Hendrickson S, Marcus HJ, Wilson MH. Prognosis of patients with bilateral fixed dilated pupils secondary to traumatic extradural or subdural haematoma who undergo surgery: a systematic review and meta-analysis. Emerg Med J. 2015;32(8):654-9. [DOI:10.1136/emermed-2014-204260] [PMID]
35. Leitgeb J, Mauritz W, Brazinova A, Majdan M, Wilbacher I. Outcome after severe brain trauma associated with epidural hematoma. Arch Orthopaed Trauma Surg. 2013;133(2):199-207. [DOI:10.1007/s00402-012-1652-y] [PMID]
| بازنشر اطلاعات | |
 |
این مقاله تحت شرایط Creative Commons Attribution-NonCommercial 4.0 International License قابل بازنشر است. |
