Volume 28, Issue 130 (September & October 2020)                   J Adv Med Biomed Res 2020, 28(130): 284-290 | Back to browse issues page

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Owlia F, Khodaei-ardakani Z, Soleymani saleh-abadi H. Assessment of Different Manifestations of Known Cases of Behçet’s Disease. J Adv Med Biomed Res 2020; 28 (130) :284-290
URL: http://journal.zums.ac.ir/article-1-6033-en.html
Assessment of Different Manifestations of Known Cases of Behçet’s Disease
Fatemeh Owlia1 , Zahra Khodaei-ardakani *2 , Hosein Soleymani saleh-abadi3
1- Dept. of Oral and Maxillofacial Medicine, School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
2- School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran , dr.owlia@gmail.com
3- associated professorDept. of Rheumatology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Abstract:   (146333 Views)

Background & Objective: Behçet’s disease (BD) is a multisystemic inflammatory vascular disorder with an autoimmune background. It is a genetic disease which can be affected by environmental factors. Behçet’s disease may involve different organs like urogenital system, skin, eyes, and gastrointestinal system. The prevalence of the disease varies considering the geographic area and genetic predisposition. This study aims to evaluate some clinical features of muco-cutaneous lesions of BD.
 Materials & Methods: This cross-sectional study was done on 43 patients with BD (24 men, 19 women). Age, sex, disease duration, and history of receiving medication were investigated. The self-reported questionnaire was completed by participants. Skin manifestations and genital and ocular involvements were also documented.
Results:  Male to female ratio was measured 1.26:1. Oral aphthous commonly localized on the lips. Ocular involvements and skin lesions prevalence percentages were 76% and 48%, respectively. There was a statically significant correlation between ocular lesions and age. Skin lesions and the frequency of oral aphthous per year had a significant relationship. There also was a significant relationship between the incidence of ocular lesions and skin lesions.
Conclusion:  Oral aphthous, the most popular manifestation of BD, is the hallmark of diagnosis. Thus, patients with oral aphthous require close surveillance for other manifestations of BD for timely diagnosis and reference to a rheumatologist.

Keywords: Aphthous, Behcets syndrome, Eye manifestations, Genitalia, Skin manifestations, Stomatitis
Full-Text [PDF 448 kb]   (155071 Downloads)    
Type of Study: Original Research Article | Subject: Clinical Medicine
Received: 2020/05/23 | Accepted: 2020/07/14 | Published: 2020/09/21
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