Volume 30, Issue 142 (September & October 2022)                   J Adv Med Biomed Res 2022, 30(142): 468-470 | Back to browse issues page


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Samiee-Rad F. Metastatic Bilateral Ovarian High Grade Serous Carcinoma to the Appendix: A Diagnosis Pitfall. J Adv Med Biomed Res 2022; 30 (142) :468-470
URL: http://journal.zums.ac.ir/article-1-6409-en.html
Dept. of Pathobiology, Clinical Research Development Unit, Kosar Hospital, Qazvin University of Medical Sciences, Qazvin, Iran , fsamieerad@gmail.com
Abstract:   (46663 Views)

Synchronized evidence of bilateral ovarian masses with an asymptomatic  incidental appendiceal solitary mass is an unusual  event during  operation.  The main differential diagnosis in this status  is metastatic mucinous adenocarcinoma of ovary to appendix  versus  metastatic mucinous neoplasm of appendix  in both side ovaries. Herein, i present a  metastatic bilateral ovarian high grade serous carcinoma to the appendix as  a diagnosis pitfall. A 43-year-old woman, with menstrual irregularity was referred. Imaging studies  showed bilateral ovarian masses. She underwent total abdominal hysterectomy, bilateral salpingo oophorectomy , omentectomy,  pelvic lymph nodes dissection and appendectomy.  Final diagnosis, according to histopathological and immunohistochemical findings was metastatic bilateral ovarian high grade serous carcinoma of the appendix. These tumor markers may be useful for final diagnosis because tumoral tissue expression of them is not 100%. Therefore usage of several of them in correlation with histopathology findings, definitely helpful.

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 These tumor markers may be useful for final diagnosis because tumoral tissue expression of them is not 100%. Therefore usage of several of them in correlation with histopathology findings, definitely helpful.


Subject: Clinical medicine
Received: 2021/01/29 | Accepted: 2022/07/27 | Published: 2022/08/8

References
1. Kinnear N, Heijkoop B, Bramwell E, et al. Communication and management of incidental pathology in 1,214 consecutive appendicectomies; a cohort study. Int J Surg. 2019;72:185-91. [DOI:10.1016/j.ijsu.2019.10.025] [PMID]
2. Brunner M, Lapins P, Langheinrich M, et al. Risk factors for appendiceal neoplasm and malignancy among patients with acute appendicitis. Int J Colorectal Dis. 2020 Jan;35(1):157-63. [DOI:10.1007/s00384-019-03453-5] [PMID]
3. Della Corte L, Giampaolino P, Fabozzi A . Breast metastasis two years after pelvic surgery and adjuvant chemotherapy for serous ovarian cancer. Gynecol Endocrinol. 2019 4;35(3):211-3. [DOI:10.1080/09513590.2018.1521795] [PMID]
4. Babaier A, Ghatage P. Mucinous cancer of the ovary: overview and current status. Diagnostics. 2020;10(1):52. [DOI:10.3390/diagnostics10010052] [PMID] [PMCID]
5. Kumar T, Khanna P, Nigam JS, Singh A, Agrawal N. Mucinous appendiceal tumor presenting as bilateral adnexal mass. J Gastrointest Cancer. 2020:1-4. [DOI:10.1007/s12029-020-00453-5] [PMID]
6. Yoon WJ, Yoon YB, Kim YJ, Ryu JK, Kim YT. Secondary appendiceal tumors: a review of 139 cases. Gut Liver. 2010;4(3):351. [DOI:10.5009/gnl.2010.4.3.351] [PMID] [PMCID]
7. Simpson GS, Mahapatra SR, Evans J. Incidental complete excision of appendiceal gastric cancer metastasis. Int J Surg Case Rep. 2013;2013(10). [DOI:10.1093/jscr/rjt080] [PMID] [PMCID]
8. Ghelichkhani M, Naffisi N, Meydansar FG, Rahimi Z, Haghighikian M, Sadeghi L. Ovarian cancer metastatic to breast and axilla: A case report. Arch Breast Can. 2020:88-92. [DOI:10.32768/abc.20207288-92]

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