Volume 32, Issue 150 (January & February 2024)                   J Adv Med Biomed Res 2024, 32(150): 67-78 | Back to browse issues page


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Jalili S, Kavandi D, Gheiasi S F. Comparison of the Effect of Adding Magnesium Sulfate and Low-Dose Dexamethasone to Ropivacaine for Supraclavicular Brachial Plexus (Trunks) Nerve Block in Elective Upper Limb Surgeries: A Prospective Triple-Blind Randomized Clinical Trial. J Adv Med Biomed Res 2024; 32 (150) :67-78
URL: http://journal.zums.ac.ir/article-1-7179-en.html
1- Dept. of Anesthesiology, School of Medicine, Ayatollah Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran
2- Dept. of Operating Room and Anesthesiology, School of Nursing and Midwifery, Zanjan University of Medical Sciences, Zanjan, Iran , fatemeh.gheiasi@gmail.com
Abstract:   (278 Views)

Background and Objective: A supraclavicular brachial plexus block (SCBPB) is a safe alternative to general anesthesia in upper limb surgeries. We compared the effect of adding magnesium sulfate (MS) and low-dose dexamethasone (LDD) to ropivacaine in SCBPB in elective upper limb surgeries. 
Materials & Methods: The ultrasound-guided SCBPB was done on 55 candidates for elective upper extremity surgeries in 3 groups by using 200 mg MS + 24 mL ropivacaine 0.5% (MS Group), 4 mg dexamethasone + 24 mL ropivacaine 0.5% (LDD Group), and 1 mL normal saline + 24 mL ropivacaine 0.5% (NS Group). The sample was investigated for the sensory and motor block onset, motor and sensory block duration, analgesia duration, total opioid consumption, and the Visual Analog Scale (VAS) during sensory return.
Results: The onset of motor and sensory block was faster in the MS group compared to the LDD and NS group (P<0.05). The sensory block duration was longer in the LDD group compared to the MS and NS groups. The duration of motor block and analgesia in the LDD group was significantly longer than the NS group (P<0.05). However, this difference was not significant regarding the MS group (p>0.05). The LDD and MS groups were not different in terms of total opioid consumption and VAS at the time of sensory return. However, both groups had significant differences with the NS group (P<0.05).
Conclusion: The LDD prolonged the motor and sensory block duration and analgesia compared to MS.

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Type of Study: Clinical Trials | Subject: Clinical medicine
Received: 2023/02/6 | Accepted: 2023/12/2 | Published: 2024/01/30

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