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1- Department of internal medicine, Zanjan university of medical science. Zanjan, Iran , dr.nooshinjalili@zums.ac.ir
2- Advanced thoracic research, Tehran University of Medical Sciences
3- Advanced thoracic research, Tehran University of Medical Sciences, Tehran. Iran
2- Advanced thoracic research, Tehran University of Medical Sciences
3- Advanced thoracic research, Tehran University of Medical Sciences, Tehran. Iran
Abstract: (143 Views)
Background and Objectives: Obstructive sleep apnea is the most common sleep-related breathing disorders characterized by repeated obstruction of the upper airways (pharynx) during sleep, which can lead to or arousal and decreased arterial oxygen saturation. This study compares apnea index < 5 with apnea index >5 in patients suffering from obstructive sleep apnea with AHI> 15.
Materials and Methods: This cross-sectional study was performed on patients with obstructive sleep apnea (OSA) in Imam Khomeini Hospital sleep lab in Tehran, Iran between 2023 and 2024. Demographic information (patient name, age, sex, menopausal status, history of smoking and psychotropic substances, history of alcohol consumption, BMI, neck circumference, and patient's blood pressure status) were recorded. Also, excessive drowsiness status using Epworth Scale questionnaire, Snoring status during sleep, ODI Saturation test, apnea index and apnea-hypopnea index, and oxygen saturation <90% during sleep was recorded. Furthermore, the type of treatment prescribed (medication, surgery, CPAP or Bilevel positive airway pressure [BiPAP]), compliance with the prescribed treatment and the number of hours (at night) and months of use of the instrument were recorded. The collected data were analyzed using SPSS statistical software version 22. A p-value less than 0.05 was statistically significant.
Results: Study population consisted of 59 females (52.7%) and 53 males (47.3%). The mean age of patients was 51±13.4 years. Furthermore,111 patients (99.1%) had no history of smoking and use of psychedelics. 32.1% of had a history of HTN. Mean BMI was 31.84 ± 7.55, mean neck circumference was 40.83. BMI and neck circumference of women were lower than men. The average ODI was 36.1, which was higher in women than men.
The mean EP worth Scale was 11.98±5, the mean AHI of patients was 43.14 ± 31.96. Of the 28 patients who provided the device, 15 had apnea less than 5 and 13 had apnea > 5. Of the 15 people with apnea less than 5, all used the instrument for more than 4 hours, and 14 continued its use after 30 months. Of the 13 people with apnea above 5, 12 were still using it for more than 4 hours and 11 after 3 months.
Conclusion: Our finding indicated that solving the problems and inability of instrument provision can be effective in increasing treatment compliance. Although a significant number of patients did not obtain the instrument, of those who did, the combination of 4 hours a day and more than 3 hours was appropriate.
Materials and Methods: This cross-sectional study was performed on patients with obstructive sleep apnea (OSA) in Imam Khomeini Hospital sleep lab in Tehran, Iran between 2023 and 2024. Demographic information (patient name, age, sex, menopausal status, history of smoking and psychotropic substances, history of alcohol consumption, BMI, neck circumference, and patient's blood pressure status) were recorded. Also, excessive drowsiness status using Epworth Scale questionnaire, Snoring status during sleep, ODI Saturation test, apnea index and apnea-hypopnea index, and oxygen saturation <90% during sleep was recorded. Furthermore, the type of treatment prescribed (medication, surgery, CPAP or Bilevel positive airway pressure [BiPAP]), compliance with the prescribed treatment and the number of hours (at night) and months of use of the instrument were recorded. The collected data were analyzed using SPSS statistical software version 22. A p-value less than 0.05 was statistically significant.
Results: Study population consisted of 59 females (52.7%) and 53 males (47.3%). The mean age of patients was 51±13.4 years. Furthermore,111 patients (99.1%) had no history of smoking and use of psychedelics. 32.1% of had a history of HTN. Mean BMI was 31.84 ± 7.55, mean neck circumference was 40.83. BMI and neck circumference of women were lower than men. The average ODI was 36.1, which was higher in women than men.
The mean EP worth Scale was 11.98±5, the mean AHI of patients was 43.14 ± 31.96. Of the 28 patients who provided the device, 15 had apnea less than 5 and 13 had apnea > 5. Of the 15 people with apnea less than 5, all used the instrument for more than 4 hours, and 14 continued its use after 30 months. Of the 13 people with apnea above 5, 12 were still using it for more than 4 hours and 11 after 3 months.
Conclusion: Our finding indicated that solving the problems and inability of instrument provision can be effective in increasing treatment compliance. Although a significant number of patients did not obtain the instrument, of those who did, the combination of 4 hours a day and more than 3 hours was appropriate.
Type of Study: Original Research Article |
Subject:
Clinical Medicine
Received: 2026/02/13 | Accepted: 2026/06/2
Received: 2026/02/13 | Accepted: 2026/06/2
References
1. Beaudin A, Waltz X, Hanly PJ, Poulin MJ. Impact of obstructive sleep apnoea and intermittent hypoxia on cardiovascular and cerebrovascular regulation. Exp. Physiol, 2017; 102: 743-63. [DOI:10.1113/EP086051] [PMID]
2. Choi J, Song JS, Lee YJ, Jeong DU. Periodic limb movements in sleep is associated with increased mortality. Psychiatr Investig. 2017; 14, 669-673. [DOI:10.4306/pi.2017.14.5.669] [PMID] [PMCID]
3. Edwards BA, Wellman A, Sands SA, Owens RL, Eckert DJ, White DP, et al. Personalized treatment approaches for obstructive sleep apnea. Am J Respir Crit Care Med. 2023;208(8):889 901.
4. Hnin Kh,Mukherjee S,Antic N,Catcheside P,Coetzer Ch,McEvoy D,et al. The impact of ethnicity on the prevalence and severity of obstructive sleep apnea. Sleep Med Rev. 2018; 4(1): 78-86. [DOI:10.1016/j.smrv.2018.01.003] [PMID]
5. da Silva P, Zhang L. Continuous positive airway pressure for adults with obstructive sleep apnea and cardiovascular disease: A meta-analysis of randomized trials. Sleep Med. 2019; 5(4): 28-34. [DOI:10.1016/j.sleep.2018.09.030] [PMID]
6. Malhotra A, Ayappa I, Ayas N, Collop N, Kirsch D, Mehra R. Advances in the diagnosis of obstructive sleep apnea. Lancet Respir Med. 2023;11(6):543 56.
7. Kapur VK, Auckley DH, Chowdhuri S, Kuhlmann DC, Mehra R, Ramar K, et al. Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea. J Clin Sleep Med. 2024;20(2):259 271.
8. Bajwah S, Ross JR, Wells AU, et al. Palliative care for patients with advanced fibrotic lung disease: a randomised controlled phase II and feasibility trial of a community case conference intervention. Thorax. 2015; 70: 8-30. [DOI:10.1136/thoraxjnl-2014-206583] [PMID]
9. Eckert DJ. Phenotypic approaches to obstructive sleep apnoea - New pathways for targeted therapy. Lancet Respir Med. 2023;11(4):321 34.
10. Ramos A, Figueredo P, Shafazand Sh, Chediak A, Abreu A, Dib S, et al.Obstructive sleep apnea phenotypes and markers of vascular disease: A review. Front Neurol, 2017; 8: 659. [DOI:10.3389/fneur.2017.00659] [PMID] [PMCID]
11. de Ruiter M, Benoist L, de Vries N , de Lange J. Durability of treatment efects of the sleep position trainer versus oral appliance therapy in positional OSA: 12- month follow-up of a randomized controlled trial. Sleep Breath. 2018; 2(4): 441-50. [DOI:10.1007/s11325-017-1568-4] [PMID] [PMCID]
12. Pelosi LB, Silveira ML, Eckeli AL, Chayamiti EM, Almeida LA, Sander HH, et al. The importance of clinical monitoring for compliance with continuous positive airway pressure. Braz J Otorhinolaryngol. 2017; 8(3): 439-44. [DOI:10.1016/j.bjorl.2016.05.013] [PMID] [PMCID]
13. Erna S. Obstructive sleep apnoea in the general population: highly prevalent but minimal symptoms, Eur Respir J. 2016; 4(7): 194-202. [DOI:10.1183/13993003.01148-2015] [PMID]
14. Gabbay I. Age- and gender-related characteristics of obstructive sleep apnea. Sleep Breath. 2012; 1(6): 453-60. [DOI:10.1007/s11325-011-0523-z] [PMID]
15. Ghosh D. Identifying poor compliance with CPAP in obstructive sleep apnoea: A simple prediction equation using data after a two-week trial. Respir Med. 2013;107 (6): 936-42. [DOI:10.1016/j.rmed.2012.10.008] [PMID]
16. Awopeju O, Fawale M, Olowookere S, Salami O, Adewole O , Erhabor G. The risk of obstructive sleep apnea and its association with indices of general and abdominal obesity in a Nigerian family practice clinic: a crosssectional study.Alexandria J Med. 2020; 56(1): 14-20. [DOI:10.1080/20905068.2019.1711304]
17. Lin H. Factors associated with noncompliance to treatment with positive airway pressure. Arch Otolaryngol Head Neck Surg. 2007;13(3): 69-72. [DOI:10.1001/archotol.133.1.69] [PMID]
18. Anttalainen U, Saaresranta T, Aittokallio J,Kalleinen N,Vahlberg T,Virtanen I, et al. Impact of menopause on the manifestation and severity of sleep-disordered breathing. Acta Obstet Gynecol Scand. 2006; 8(5): 1381-88. [DOI:10.1080/00016340600935649] [PMID]
19. Kim J. Compliance with positive airway pressure treatment for obstructive sleep apnea, Clin Experiment Otorhinolaryngol. 2009; 2(2): 90-96. [DOI:10.3342/ceo.2009.2.2.90] [PMID] [PMCID]
20. Hayashi Sh , Tamaoka M , Tateishi T , Murota Y , Handa I, Miyazaki Y.A new feature with the potential to detect the severity of obstructive sleep apnoea via snoring sound analysis.Int J Environ Res Public Health. 2020; 1(7): 29- 51. [DOI:10.3390/ijerph17082951] [PMID] [PMCID]
21. Kribbs NB, Pack AI, Kline LR, Smith PL, Schwartz AR, Schubert NM, et al. Objective measurement of patterns of nasal CPAP use by patients with obstructive sleep apnea. Am Rev Respir Dis. 1993; 147(4): 887-95. [DOI:10.1164/ajrccm/147.4.887] [PMID]
22. McArdle N, Devereux G, Heidarnejad H, Engleman HM, Mackay TW, Douglas NJ. Long-term use of CPAP therapy for sleep apnea/hypopnea syndrome. Am J Respir Crit Care Med. 1999; 15(9): 1108-14. [DOI:10.1164/ajrccm.159.4.9807111] [PMID]
23. Claudio W , Dibur E, Salomone C, Bartolo C. Compliance with continuos positive airway pressure in patients with sleep apnea/hypopnea syndrome.Medicina. 2004;64(5):395-9
24. Ayas N , Patel S, Malhotra A, Schulzer M, Malhotra M, Jung D, et al. Auto-titrating versus standard continuous positive airway pressure for the treatment of obstructive sleep apnea: results of a meta-analysis. Sleep. 2004; 27(2): 249-53. [DOI:10.1093/sleep/27.2.249] [PMID]
25. Hui DS, Choy DK, Li TS, Ko FW, Wong KK, Chan JK, et al. Determinants of continuous positive airway pressure compliance in a group of Chinese patients with obstructive sleep apnea. Chest. 2001; 120(1): 170e6. [DOI:10.1378/chest.120.1.170] [PMID]
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