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J Adv Med Biomed Res 2021, 29(135): 238-245 |
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Azimi M, Mojahedi M, Mokaberinejad R, Hasheminasab F S. Ethnomedicine Knowledge of Iranian Traditional Healers and the Novel Coronavirus Disease 2019 (COVID-19). J Adv Med Biomed Res 2021; 29 (135) :238-245
URL: http://journal.zums.ac.ir/article-1-6208-en.html
URL: http://journal.zums.ac.ir/article-1-6208-en.html
1- Gastroenterology and Hepatology Research Center, Kerman University of Medical Sciences, Kerman, Iran
2- Traditional Medicine and History of Medical Sciences Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
3- Dept. of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4- Pharmacology Research Center, Zahedan University of Medical Sciences, Zahedan, Iran ,hashemifa67@gmail.com
2- Traditional Medicine and History of Medical Sciences Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
3- Dept. of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4- Pharmacology Research Center, Zahedan University of Medical Sciences, Zahedan, Iran ,
Abstract: (136308 Views)
Background and Objective: In December 2019, the outbreak of coronavirus disease 2019 (COVID-19) was observed in China, and it it spread rapidly throughout the world. Iranian traditional healers have applied different medicinal plants to prevent and treat COVID-19 based on their ethnopharmacological knowledge. This research aimed to investigate the ethnomedicinal knowledge of Iranian traditional healers to alleviate COVID-19 signs and symptoms.
Materials and Methods: Due to the limitations caused by COVID-19 pandemic, oral interviews were conducted by 26 traditional healers in Kerman and Zahedan cities in Iran. The names of recommended remedies for COVID-19 were collected, and their scientific names were authenticated. Next, a comprehensive research was carried out in the scientific databases. Finally, the herbs with any related proved properties to the respiratory system were listed; these herbs were probably useful for the COVID-19 prevention or treatment.
Results: Zataria multiflora, Althaea officinalis, Hordeum vulgare, Malva sylvestris, Matricaria chamomilla, Glycyrrhiza glabra, Allium sativum and Zingiber officinale are considered as the most popular herbs by Iranian traditional healers for prevention and/or treatment of COVID-19. Recent studies have demonstrated that the above-mentioned herbs can be considered as good sources for alleviating the respiratory disorders such as influenza. Moreover, they have antitussive and immune-modulatory properties.
Conclusion: Since there is no effective treatment for COVID-19, the capacity of different traditional medicine and ethnomedicine knowledge can be used as good sources for new drug discovery after accurate studies.
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✅ Since there is no effective treatment for COVID-19, the capacity of different traditional medicine and ethnomedicine knowledge can be used as good sources for new drug discovery after accurate studies.
Type of Study: Original Research Article |
Subject:
Clinical Medicine
Received: 2020/09/7 | Accepted: 2021/01/19 | Published: 2021/02/28
Received: 2020/09/7 | Accepted: 2021/01/19 | Published: 2021/02/28
References
1. Lai CC, Shih TP, Ko WC, Tang HJ, Hsueh P-R. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and corona virus disease-2019 (COVID-19): the epidemic and the challenges. Int J Antimicrob Agents. 2020:105924. [DOI:10.1016/j.ijantimicag.2020.105924]
2. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet. 2020;395(10223):497-506. [DOI:10.1016/S0140-6736(20)30183-5]
3. http://dme.behdasht.gov.ir/uploads/Dastoor_Keshvari.pdf.
4. Qiu R, Wei X, Zhao M, et al. Outcome reporting from protocols of clinical trials of Coronavirus disease 2019 (COVID-19): a review. medRxiv. 2020. [DOI:10.1101/2020.03.04.20031401]
5. Luo H, Tang Ql, Shang Yx, et al. Can Chinese medicine be used for prevention of corona virus disease 2019 (COVID-19)? A review of historical classics, research evidence and current prevention programs. Chin J Integr Med. 2020:1-8. [DOI:10.1007/s11655-020-3192-6]
6. Fjær EL, Landet ER, McNamara CL, Eikemo TA. The use of complementary and alternative medicine (CAM) in Europe. BMC Complement Med Therap. 2020;20:1-9. [DOI:10.1186/s12906-020-02903-w]
7. Jalali A, Raesi Vanani A, Shirani M. Ethnobotanical approaches of traditional medicinal plants used in the management of asthma in Iran. Jundishapur J Nat Pharmaceut Product. 2020;15(1). e62269 [DOI:10.5812/jjnpp.62269]
8. Zu ZY, Jiang MD, Xu PP, et al. Coronavirus Disease 2019 (COVID-19): A Perspective from China. Radiology. 2020:200490. [DOI:10.1148/radiol.2020200490]
9. Cui HT, Li YT, Guo LY, et al. Traditional chinese medicine for treatment of coronavirus disease 2019: a review. Trad Med Res. 2020;5(2):65-73.
10. Ghamarian AR HM, Javadi M. Physicians Desk Refrence. Tehran: Clinical pharmacy Department, Tehran University of Medical Sciences; 2011-2012.
11. Boskabady M, Jandaghi P. Relaxant effects of carvacrol on guinea pig tracheal chains and its possible mechanisms. Die Pharmazie. 2003;58(9):661-3.
12. Kemmerich B. Evaluation of efficacy and tolerability of a fixed combination of dry extracts of thyme herb and primrose root in adults suffering from acute bronchitis with productive cough. Arzneimittelforschung. 2007;57(09):607-15. [DOI:10.1055/s-0031-1296656]
13. Shokri H, Asadi F, Bahonar AR, Khosravi AR. The role of Zataria multiflora essence (Iranian herb) on innate immunity of animal model. Iran J Immunol. 2006;3(4):164-8.
14. Shayeganmehr A, Vasfi Marandi M, Karimi V, Barin A, Ghalyanchilangeroudi A. Zataria multiflora essential oil reduces replication rate of avian influenza virus (H9N2 subtype) in challenged broiler chicks. Br Poult Sci. 2018;59(4):389-95. [DOI:10.1080/00071668.2018.1478064]
15. Hosseini F, Mahjoub H, Amanati A, Fazlian MM, Sedighi I. Comparison of zataria multiflora extract syrup and diphenhydramine in the treatment of common cold-induced cough in children: A double-blind, randomized, clinical trial. Arch Pediatr Infect Dis. 2016;4(3). [DOI:10.5812/pedinfect.35495]
16. Nosal'ova G, Strapkova A, Kardosova A, Capek P, Zathurecký L, Bukovská E. Antitussive action of extracts and polysaccharides of marsh mallow (Althea officinalis L., var. robusta). Die Pharmazie. 1992;47(3):224-6.
17. Yamada H, Nagai T, Cyong JC, et al. Relationship between chemical structure and anti-complementary activity of plant polysaccharides. Carbohydr Res. 1985;144(1):101-11. [DOI:10.1016/0008-6215(85)85011-4]
18. Derakhshan A, Khodadoost M, Ghanei M, et al. Effects of a novel barley-based formulation on allergic rhinitis: A randomized controlled trial. Endocr Metab Immune Disord Drug Targets. 2019;19(8):1224-31. [DOI:10.2174/1871530319666190306100611]
19. Nagai E, Iwai M, Koketsu R, et al. Anti-influenza virus activity of Adlay Tea Components. Plant Foods Hum Nutr. 2019;74(4):538-43. [DOI:10.1007/s11130-019-00773-3]
20. Bilen S, Filogh AMO, Ali AB, Kenanoğlu ON, Zoral MA. Effect of common mallow (Malva sylvestris) dietary supplementation on growth performance, digestive enzyme activities, haemotological and immune responses of common carp (Cyprinus carpio). Aquaculture Int. 2020;28(1):73-84. [DOI:10.1007/s10499-019-00444-9]
21. Cesaro C, Cautiero T, Cautiero V, et al. Therapeutic efficacy of hyaluronic acid, N-acetylcysteine and chamomile aerosolized in chronic cough of COPD patients (GOLD stage III-IV). Minerva Pneumol. 2014;53(1):15-20.
22. Haggag EG, Abou-Moustafa MA, Boucher W, Theoharides TC. The effect of a herbal water-extract on histamine release from mast cells and on allergic asthma. J Herb Pharmacother. 2003;3(4):41-54. [DOI:10.1080/J157v03n04_03]
23. Cinatl J, Morgenstern B, Bauer G, Chandra P, Rabenau H, Doerr H. Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus. The Lancet. 2003;361(9374):2045-6. [DOI:10.1016/S0140-6736(03)13615-X]
24. Liang S, Li M, Yu X, et al. Synthesis and structure-activity relationship studies of water-soluble β-cyclodextrin-glycyrrhetinic acid conjugates as potential anti-influenza virus agents. Eur J Med Chem. 2019;166:328-38. [DOI:10.1016/j.ejmech.2019.01.074]
25. Ghaemi H, Masoompour SM, Afsharypuor S, et al. The effectiveness of a traditional Persian medicine preparation in the treatment of chronic cough: A randomized, double-blinded, placebo-controlled clinical trial. Complement Ther Med. 2020;49. [DOI:10.1016/j.ctim.2020.102324]
26. Hussain K, Iqbal Z, Abbas RZ, Khan MK, Saleemi MK. Immunomodulatory activity of Glycyrrhiza glabra extract against mixed Eimeria infection in chickens. Int J Agric Biol. 2017;19(4):928-32. [DOI:10.17957/IJAB/15.0397]
27. Tsai Y, Cole LL, Davis LE, Lockwood SJ, Simmons V, Wild GC. Antiviral properties of garlic: in vitro effects on influenza B, herpes simplex and coxsackie viruses. Planta Med. 1985;51(05):460-1. [DOI:10.1055/s-2007-969553]
28. Ahmadniaye Motlagh H, Safari O, Selahvarzi Y, Baghalian A, Kia E. Non-specific immunity promotion in response to garlic extract supplemented diets in female Guppy (Poecilia reticulata). Fish Shellfish Immunol. 2020;97:96-9. [DOI:10.1016/j.fsi.2019.12.007]
29. Bera K, Nosalova G, Sivova V, Ray B. Structural elements and cough suppressing activity of polysaccharides from Zingiber officinale rhizome. Phytother Res. 2016;30(1):105-11. [DOI:10.1002/ptr.5508]
30. Park KJ, Lee HH. In vitro antiviral activity of aqueous extracts from Korean medicinal plants against influenza virus type A. J Microbiol Biotechnol. 2005;15(5):924-9.
31. Fadeifard F, Raissy M, Jafarian M, Boroujeni HR, Rahimi M, Faghani M. Effects of black seed (Nigella sativa), ginger (Zingiber officinale) and cone flower (Echinacea angustifolia) on the immune system of rainbow trout, Oncorhynchus mykiss. Arq Bras Med Vet Zootec. 2018;70(1):199-204. [DOI:10.1590/1678-4162-8489]
32. Wang Z, Li L, Yan J, Yao Y. Evaluating the traditional chinese medicine (TCM) officially recommended in China for COVID-19 using ontology-based side-effect prediction framework (OSPF) and deep learning. Preprints .2020. 2020020230 [DOI:10.20944/preprints202002.0230.v1]
33. Hasheminasab F, Sharififar F, Hashemi S, Setayesh M. An evidence-based research on botanical sources for oral mucositis treatment in traditional persian medicine. Curr Drug Discov Technol. 2020. [DOI:10.2174/1570163817666200203110803]
34. Hasheminasab FS, Tajadini H, Setayesh M. An evidence-based study on pharmacological treatments of non-alcoholic fatty liver disease based on traditional persian medicine. Curr Tradit Med. 2020;6(3):188-202. [DOI:10.2174/2215083805666190902114137]
35. Avicenna H. The canon of medicine (Al-Qanon fi al-Tibb). Beirut, Lebanon: Dar Ihyaa al-Turaath al-Arabi. 2005.
36. Al-Shamma A, Drake S, Flynn D, et al. Antimicrobial agents from higher plants. Antimicrobial agents from Peganum harmala seeds. J Nat Prod (Gorakhpur). 1981;44(6):745-7. [DOI:10.1021/np50018a025]
37. Hooper D, McNair JB, Field H. Useful plants and drugs of Iran and Iraq: Fieldiana Life Earth. Chicago,1937.
38. Azizi-Fini I, Adib-Hajbaghery M, Gharehboghlou Z. Herbal medicine use among patients with type 2 diabetes in Kashan, Iran, 2015. Eur J Integr Med. 2016;8(4):570-5. [DOI:10.1016/j.eujim.2016.04.003]
39. Heydari M, Heydari H, Saadati A, Gharehbeglou M, Tafaroji J, Akbari A. Ethnomedicine for neonatal jaundice: A cross-sectional survey in Qom, Iran. J Ethnopharmacol. 2016;193:637-42. [DOI:10.1016/j.jep.2016.10.019]
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