✅ The analysis showed that only LTRT among the types of exercise can elevate irisin concentration. Therefore, LTRT seems to have more beneficial influences, compared to other modes of exercise in inclusive irisin responses.

✅ The present findings suggested that oral administration of D. sophia seed extract has protective effect against acetaminophen nephrotoxicity in mice.

✅ Female sex is a global well-established hypothyroidism-associated factor. The results of the present study suggest taking some measures to reduce hypothyroidism, by addressing the intervening factors.

✅ Based on the observed antibacterial property and angiogenesis influence, PCL-GO-VEGF can be considered as a candidate to promote diabetic wound healing.

✅ Age cannot be controlled so that CVDs are mainly attributed to high blood pressure. Therefore, blood pressure control should be considered as a primary strategy to reduce CVD incidence.

✅ In conclusion, our study indicated a mutation in the PEX1 in the affected family. This mutation is a missense variant at codon 843 in ZS patients. It has an autosomal recessive inheritance pattern. This mutation may be widespread among Iranian population with ZS and can be used for a more desirable personalized medicine.

✅ Identification of diagnostic criteria has become the standard approach for disease modeling; it helps to design decision support tools. After analyzing and comparing six diagnostic performance measures, we observed that these variables have a high diagnostic power for COVID-19 detection.

✅ This study aimed to report histopathological features and serological outputs of the lung, heart and liver in a patient suffered from Coronavirus disease-2019 (COVID-19).