پنجشنبه 14 فروردین 1404
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دوره 32، شماره 152 - ( 3-1403 )
جلد 32 شماره 152 صفحات 208-202 |
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tabatabaei F, mellat A, esmaeli A, Mohammad Karimi N, nikouyeh M. Comparison of the Effect of 5 and 10% Intranasal Lidocaine Spray on Improving Headache in Patients with Head Trauma Referring to the Emergency Department. J Adv Med Biomed Res 2024; 32 (152) :202-208
URL: http://journal.zums.ac.ir/article-1-7401-fa.html
URL: http://journal.zums.ac.ir/article-1-7401-fa.html
Comparison of the Effect of 5 and 10% Intranasal Lidocaine Spray on Improving Headache in Patients with Head Trauma Referring to the Emergency Department. Journal of Advances in Medical and Biomedical Research. 1403; 32 (152) :202-208
چکیده: (368 مشاهده)
Background & Objective: Headache is a common complaint among traumatic patients referring to the emergency department. To improve headache in these patients, an effective, fast-acting, accessible and inexpensive drug without a significant effect on the level of consciousness and vital signs is highly needed.
Materials & Methods: In this double-blind randomized clinical trial (RCT) on patients with head trauma, Group A was given 5% intranasal lidocaine spray while group B was prescribed 10% intranasal lidocaine spray to improve headache. Headache severity was checked based on numeric pain scale (NPS) before drug administration and then at 5, 15, 30 minutes and plus 1 hour post-drug administration, along with patient satisfaction and possible side effects. Finally, the obtained data were analyzed using SPSS 23 software.
Results: According to the data, the maximum reduction in headache occurred 5 minutes after the drug administration. There was a significant difference between the two groups in terms of satisfaction (P value = 0.022), where group A had 100% high satisfaction while group B had 87.5% high satisfaction and 12.5% had moderate satisfaction. Of the 80 patients in the study, 3 patients had tearing complications after medication administration, which resolved after 5 minutes, and one case had nasal mucosal anesthesia, which improved after 15 minutes.
Conclusion: According to the results of this study, the use of 5% intranasal lidocaine spray is as effective as 10% intranasal lidocaine spray in relieving headache in traumatic patients and was associated with greater satisfaction and fewer complications.
Materials & Methods: In this double-blind randomized clinical trial (RCT) on patients with head trauma, Group A was given 5% intranasal lidocaine spray while group B was prescribed 10% intranasal lidocaine spray to improve headache. Headache severity was checked based on numeric pain scale (NPS) before drug administration and then at 5, 15, 30 minutes and plus 1 hour post-drug administration, along with patient satisfaction and possible side effects. Finally, the obtained data were analyzed using SPSS 23 software.
Results: According to the data, the maximum reduction in headache occurred 5 minutes after the drug administration. There was a significant difference between the two groups in terms of satisfaction (P value = 0.022), where group A had 100% high satisfaction while group B had 87.5% high satisfaction and 12.5% had moderate satisfaction. Of the 80 patients in the study, 3 patients had tearing complications after medication administration, which resolved after 5 minutes, and one case had nasal mucosal anesthesia, which improved after 15 minutes.
Conclusion: According to the results of this study, the use of 5% intranasal lidocaine spray is as effective as 10% intranasal lidocaine spray in relieving headache in traumatic patients and was associated with greater satisfaction and fewer complications.
نوع مطالعه: کارآزمایی بالینی |
موضوع مقاله:
Clinical Medicine
دریافت: 1402/9/16 | پذیرش: 1403/6/11 | انتشار: 1403/4/1
دریافت: 1402/9/16 | پذیرش: 1403/6/11 | انتشار: 1403/4/1
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