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Volume 32, Issue 152 (May & June 2024)
J Adv Med Biomed Res 2024, 32(152): 202-208 |
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tabatabaei F, mellat A, esmaeli A, Mohammad Karimi N, nikouyeh M. Comparison of the Effect of 5 and 10% Intranasal Lidocaine Spray on Improving Headache in Patients with Head Trauma Referring to the Emergency Department. J Adv Med Biomed Res 2024; 32 (152) :202-208
URL: http://journal.zums.ac.ir/article-1-7401-en.html
URL: http://journal.zums.ac.ir/article-1-7401-en.html
1- department of Emergency Medicine, School of Medicine, Shahid sadoughi University of Medical Sciences, Yazd, Iran
2- Department of Neurology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
3- department of Emergency Medicine, School of Medicine, Shahid sadoughi University of Medical Sciences, Yazd, Iran ,alirezaesmaeili1@ssu.ac.ir
4- Department of Emergency Medicine, School of Medicine, Shahid sadoughi University of Medical Sciences, Yazd, Irad
2- Department of Neurology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
3- department of Emergency Medicine, School of Medicine, Shahid sadoughi University of Medical Sciences, Yazd, Iran ,
4- Department of Emergency Medicine, School of Medicine, Shahid sadoughi University of Medical Sciences, Yazd, Irad
Abstract: (130 Views)
Background & Objective: Headache is a common complaint among traumatic patients referring to the emergency department. To improve headache in these patients, an effective, fast-acting, accessible and inexpensive drug without a significant effect on the level of consciousness and vital signs is highly needed.
Materials & Methods: In this double-blind randomized clinical trial (RCT) on patients with head trauma, Group A was given 5% intranasal lidocaine spray while group B was prescribed 10% intranasal lidocaine spray to improve headache. Headache severity was checked based on numeric pain scale (NPS) before drug administration and then at 5, 15, 30 minutes and plus 1 hour post-drug administration, along with patient satisfaction and possible side effects. Finally, the obtained data were analyzed using SPSS 23 software.
Results: According to the data, the maximum reduction in headache occurred 5 minutes after the drug administration. There was a significant difference between the two groups in terms of satisfaction (P value = 0.022), where group A had 100% high satisfaction while group B had 87.5% high satisfaction and 12.5% had moderate satisfaction. Of the 80 patients in the study, 3 patients had tearing complications after medication administration, which resolved after 5 minutes, and one case had nasal mucosal anesthesia, which improved after 15 minutes.
Conclusion: According to the results of this study, the use of 5% intranasal lidocaine spray is as effective as 10% intranasal lidocaine spray in relieving headache in traumatic patients and was associated with greater satisfaction and fewer complications.
Materials & Methods: In this double-blind randomized clinical trial (RCT) on patients with head trauma, Group A was given 5% intranasal lidocaine spray while group B was prescribed 10% intranasal lidocaine spray to improve headache. Headache severity was checked based on numeric pain scale (NPS) before drug administration and then at 5, 15, 30 minutes and plus 1 hour post-drug administration, along with patient satisfaction and possible side effects. Finally, the obtained data were analyzed using SPSS 23 software.
Results: According to the data, the maximum reduction in headache occurred 5 minutes after the drug administration. There was a significant difference between the two groups in terms of satisfaction (P value = 0.022), where group A had 100% high satisfaction while group B had 87.5% high satisfaction and 12.5% had moderate satisfaction. Of the 80 patients in the study, 3 patients had tearing complications after medication administration, which resolved after 5 minutes, and one case had nasal mucosal anesthesia, which improved after 15 minutes.
Conclusion: According to the results of this study, the use of 5% intranasal lidocaine spray is as effective as 10% intranasal lidocaine spray in relieving headache in traumatic patients and was associated with greater satisfaction and fewer complications.
Type of Study: Clinical Trials |
Subject:
Clinical medicine
Received: 2023/12/7 | Accepted: 2024/09/1 | Published: 2024/06/21
Received: 2023/12/7 | Accepted: 2024/09/1 | Published: 2024/06/21
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