Volume 30, Issue 143 (November & December 2022)  

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 In general, antioxidant supplements may be able to help prevent, treat, and improve the prognosis of this disease, which requires further research in this area.



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 Tumor-resident mesenchymal stem cells can promote colorectal cancer metastasis inducing EMT as well as increasing cancer stem cell frequency in the tumor microenvironment. It seems that direct contact between MSCs and colorectal cancer cells is not required for the interaction. Our findings may help scientists to find effective strategies against cancer metastasis by targeting tumor-resident MSCs.



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 This study showed no effect of adding methylprednisolone and interferon beta to the treatment protocol on mortality in the patients.



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 This study's outcomes illustrate that parents of more than half of children with genetic disorders had consanguinity and the frequency of consanguinity was more common in parents of children with molecular disease than chromosomal disorder. Given that, it is necessary to avoid consanguineous marriage as much as possible, and families with a history of molecular genetic disease, should be informed of the possible consequences.



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 In this study the severity of COVID-19 disease in kidney patients was measured using variables including age, diabetes mellitus, blood pressure, CKD stage, etc. The results showed that high levels of kidney disease can lead to severe COVID-19.



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 Most of the patients with T2DM had an inadequate PAL. Compared with low and high PALs, moderate PAL might have lowered the incidence of COVID-19 more effectively. Finally, a moderate PAL is recommended to patients with T2DM to boost the immune system and prevent COVID-19 infection than high or low PAL.



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 Male sex, older age, lymphopenia, hypernatremia, increased Urea, increased LDH, and hyperglycemia may serve as potential risk factors for in-hospital death. D-dimer and CK-MB may be used in identifying patients with high probability of in-hospital death. These tests may be used in clinical decision-making in order to improve outcomes of patients with COVID-19.



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 Breast milk is a rich source of beneficial probiotic lactobacilli, which can be useful in breast milk for infants who are not breastfed to prevent neonatal infections.



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 In this study, aminoglycoside-resistant A. baumannii was found in a high percentage of ICU patients, mainly with the enzyme-modified aminoglycosides like aac(6′)-Ib, aph(2'')-Id and ant(3'')-I. ERIC-PCR has also shown an increased level of diversity in A. baumannii isolates. Therefore, genetic diversity or clonal relatedness of A. baumannii isolates in clinical settings can be assessed using ERIC-PCR.



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 The findings suggest that R. turkestanicum extract has neuroprotective activity on 6-OHDA-induced neuronal toxicity of neuroblastoma cells.



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 The study findings suggest that D. stramonium extract is effective in alleviating the signs of morphine withdrawal. Additional research is needed to determine the exact mechanisms underlying D. stramonium for inhibiting morphine withdrawal syndrome.



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 In this article, we have reported the reconstruction of a traumatic scalp defect in a one-year-old baby. There was a large defect in the left temporoparietal area of the scalp. The wound was debrided and irrigated with normal saline frequently.



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 We herein describe a 34-year-old woman with a persistent left superior vena cava (PLSVC) impinging on the posterior wall of the left atrium, subdivided by a membrane at the distal part of the impingement.



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 In summary, the condition of COVID-19-infected patients (moderate form) might be worsened by physical activity, even for small personal tasks. Clinicians should consider complete bed rest to overcome this obstacle appropriately. Furthermore, physical activity guidelines to patients should be prepared by specialist during infection period and after relief of diseases.




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