Mon, Aug 17, 2026
[Archive]
Articles In Press
Back to the articles list |
Back to browse issues page
1- Food and Beverages Safety Research Center, Urmia University of Medical Sciences, Urmia, Iran
2- Department of Psychology, Stockholm University, Stockholm, Sweden
3- Nephrology and Kidney Transplant Research Center, Clinical Research Institute, Urmia University of Medical Sciences, Urmia, Iran & Department of Physiology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran ,r_naderi_s@yahoo.com
2- Department of Psychology, Stockholm University, Stockholm, Sweden
3- Nephrology and Kidney Transplant Research Center, Clinical Research Institute, Urmia University of Medical Sciences, Urmia, Iran & Department of Physiology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran ,
Abstract: (8 Views)
Erectile dysfunction in male patients receiving MMT is a complex condition influenced by both biological and psychological factors. Methadone's effect on hormonal balance and the nervous system can disrupt sexual function, while mental health issues related to addiction and recovery can exacerbate the issue. An effective management plan should include hormonal assessment, psychological support, pharmacological therapy, and patient education. Encouraging healthier lifestyle choices and addressing both the physical and emotional aspects of ED can significantly enhance sexual health and overall quality of life for individuals in treatment for substance abuse.
Type of Study: Letter to the Editor |
Subject:
Clinical Medicine
Received: 2025/07/18 | Accepted: 2026/06/16
Received: 2025/07/18 | Accepted: 2026/06/16
References
1. Mirzaei S, Yazdi-Feyzabadi V, Mehrolhassani MH, Nakhaee N, Oroomiei N. Unveiling the roadblocks: exploring substance use disorder treatment policies in Iran through a qualitative lens. Addict Sci Clin Pract. 2024;19(1):80. [DOI:10.1186/s13722-024-00511-4] [PMID] [PMCID]
2. Aghakhani N, Lopez V, Cleary M. Experiences and perceived social support among Iranian men on methadone maintenance therapy: a qualitative study. Issues Ment Health Nurs. 2017;38(9):692-97. [DOI:10.1080/01612840.2017.1341586] [PMID]
3. Gerra G, Manfredini M, Somaini L, Maremmani I, Leonardi C, Donnini C. Sexual dysfunction in men receiving methadone maintenance treatment: clinical history and psychobiological correlates. Eur Addict Res. 2016;22(3):163-75. [DOI:10.1159/000441470] [PMID]
4. Trajanovska AS, Vujovic V, Ignjatova L, Janicevic-Ivanovska D, Cibisev A. Sexual dysfunction as a side effect of hyperprolactinemia in methadone maintenance therapy. Med Arch. 2013;67(1):48-50. [DOI:10.5455/medarh.2013.67.48-50] [PMID]
5. Changchien TC, Hsieh TJ, Yen YC. Erectile dysfunction among male patients receiving methadone maintenance treatment: focusing on anxiety-related symptoms. Sex Med. 2024;12(4): qfae052. [DOI:10.1093/sexmed/qfae052] [PMID] [PMCID]
6. Ramli FF, Shuid AN, Pakri Mohamed RM, Tg Abu Bakar Sidik TMI, Naina Mohamed I. Health-seeking behavior for erectile dysfunction in methadone maintenance treatment patients. Int J Environ Res Public Health. 2019;16(21):4249. [DOI:10.3390/ijerph16214249] [PMID] [PMCID]
7. Bruneau J, Ahamad K, Goyer MÈ, Poulin G, Selby P, Fischer B, Wild TC, Wood E; CIHR Canadian Research Initiative in Substance Misuse. Management of opioid use disorders: a national clinical practice guideline. CMAJ. 2018;190(9):E247-E257. [DOI:10.1503/cmaj.170958] [PMID]
8. Motazedian S, Entezam S, Banihashem S, Zahed G, Kheradmand A. Erectile dysfunction in methadone maintenance therapy.Int J High Risk Behav Addict.2020;9(3):e100781. [DOI:10.5812/ijhrba.100781]
9. Hammarlund R, Crapanzano KA, Luce L, Mulligan L, Ward KM. Review of the effects of self-stigma and perceived social stigma on the treatment-seeking decisions of individuals with drug- and alcohol-use disorders. Subst Abuse Rehabil. 2018;9:115-136. [DOI:10.2147/SAR.S183256] [PMID] [PMCID]
10. Medina II WA, Conermann T. Opioid-induced endocrinopathy. [Updated 2022 Nov 15]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK559211/
11. Cai Z, Song X, Zhang J, Yang B, Li H. Practical approaches to treat ED in PDE5i nonresponders. Aging Dis. 2020;11(5):1202-1218. [DOI:10.14336/AD.2019.1028] [PMID] [PMCID]
12. Durrani M, Bansal K. Methadone. [Updated 2024 Jan 11]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK562216/
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
Copyright Policy
Journal of Advances in Medical and Biomedical Research by Farname Inc. is licensed under CC BY-NC 4.0
