Volume 31, Issue 149 (November & December 2023)  

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Abstract (2023 Views) | Full-Text (PDF) (546 Downloads)   |   Full-Text (HTML) (490 Views)   |   Highlights

In this review, data on oxidative stress and inflammation is compiled and discussed in the context of chronic neuropathic pain.It is suggested that oxidative stress can activate a variety of pro-inflammatory factors involved in chronic diseases.



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Following our model validation using the existing experimental data, our model suggested critical molecules and candidate medicines involve in  surfactant function in rejection of lung transplantation for furtur investigations.



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Using a spreader graft in the primary rhinoplasty of patients with less than 3mm hump reduction, without causing serious complications, increases the patient’s satisfaction with dorsum aesthetics.



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HPLT combined with the routine physiotherapy improve the clinical as well as sonography findings including supraspinatus tendon thickness and accumulation of sub-acromial fluid in people with rotator cuff tendinitis compared with those in the control group.



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Pregnant women with RA are more likely to experience spontaneous abortion, cesarean section, and having LBW infants comparing to pregnant women without RA.



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When clients and their families bear the full cost of treatment, cost payers' income plays a key role in preparedness for purchasing treatment services. The severity of substance use disorder is the second factor determining WTP for treatment.



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The present study, to date, is the first to investigate HSP27 gene expression levels in COVID-19 patients. Conducting further studies on HSP27 is of considerable help to clarify the importance of this molecule in SARS-CoV-2 infection.



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Our findings indicate that hPMSC-MVs induce Cell death pathways of autophagy and apoptosis in the KG1 cell lines. Additionally, hPMSC-MVs exhibited heightened impactful anti-proliferative and pro-apoptotic outcomes on KG1 cells in vitro.



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Due to the presence of β-carbolines, the P. harmala seed extract has toxicity and affects insulin secretion and C-peptide uptake secretion at lower concentrations than those of leaf extract.



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This study revealed possible specific exonic targets of components of the SHH signaling pathway through designing proper sgRNAs using the CRISPR/Cas9 genome editing approach.



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There was a positive relationship between DAS-28ESR and Tripartite motif-containing protein 72 levels, which induces bone erosion. The serum Tripartite motif-containing protein 72 level showed a significant elevation in rheumatoid arthritis patients compared with healthy controls. Tripartite motif-containing protein 72 had a poor discriminative ability between RA and the control group.



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This study reports clinical laboratory, radiological, and magnetic resonance imaging (MRI) findings as well as whole-exome sequencing (WES) of a female patient aged 19 months and 7 days with encephalopathy. The limitation of this study such as lack of access to the patients or biological samples of other similar patients hindered further evaluation. Hence, comprehensive research must be conducted to reveal the underlying etiology.




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