Volume 19, Issue 74 (3-2011)                   J Adv Med Biomed Res 2011, 19(74): 17-24 | Back to browse issues page

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Sadeghzadeh M, khoshnevis Asl P, mousavinasab S N, Koosha A, Norouzi Pakdel M. The Relation Between Serum Zinc Level and Febrile Seizures in Children Admitted to Zanjan Valie-Asr Hospital. J Adv Med Biomed Res 2011; 19 (74) :17-24
URL: http://journal.zums.ac.ir/article-1-1412-en.html
The Relation Between Serum Zinc Level and Febrile Seizures in Children Admitted to Zanjan Valie-Asr Hospital
Mansour Sadeghzadeh * 1, Parisa Khoshnevis Asl2 , Seyed Norodin Mousavinasab2 , Ali Koosha3 , Mahmoud Norouzi Pakdel4
1- Dept. of Pediatrics, Zanjan University of Medical Sciences, Zanjan, Iran , m39sadegh@yahoo.com
2- Dept. of Pediatrics, Zanjan University of Medical Sciences, Zanjan, Iran
3- Dept. of Social Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
4- 22 Bahman Hospital, Tabriz, Iran
Abstract:   (166390 Views)

Background and Objective: Febrile seizures (FS) are the most common seizures seen in childhood with a prevalence of 2-14% in different societies. This study was carried out regarding the possibility of the relationship between serum zinc levels and occurrence of FS.
Materials and Methods: 117 children ranging from 6 months to 5 years were divided into four groups: FS (n=39), febrile patients with no seizures (FNS) (n=40), control group of afebrile patients with no seizures (AFNS) (n=32), and patients with seizures without fever (n=6). After completion of a questionnaire and obtaining blood, serum zinc levels were measured. Data was analyzed using SPSS software.
Results: The mean serum zinc levels in 39 FS patients was 75.67 mcg/dl, 40 febrile patients with no seizure had a mean serum zinc level of 87.58 mcg/dl. 32 afebrile patients with no seizure had a mean serum zinc level of 89.06  mcg/dl and in 6 afebrile patients with seizure; the mean serum zinc level was 96/67 mcg/dl. The serum zinc level in FS patients was significantly lower than the other groups (p=0.002 and p=0.001), whereas the 3 other groups had no significant difference (P= 0.971).
Conclusion: Regarding the high incidence of hypozincaemia in FS, low serum zinc levels may be associated with the occurrence of FS.

Keywords: Febrile Seizures, Serum Zinc Leuel, Febrile Patients, Zanjan
Full-Text [PDF 184 kb]   (159211 Downloads)    
Type of Study: Original Article |
Received: 2011/03/8 | Accepted: 2014/06/23 | Published: 2014/06/23
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