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Volume 10, Issue 38 (3-2002)
J Adv Med Biomed Res 2002, 10(38): 7-11 |
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Borji A, Shahraki S, Etemadi H. Proteus Mirabilis & Its Implication In Struvite Urolithiasis. J Adv Med Biomed Res 2002; 10 (38) :7-11
URL: http://journal.zums.ac.ir/article-1-415-en.html
URL: http://journal.zums.ac.ir/article-1-415-en.html
Abstract: (149128 Views)
Background: Urinary stones are widely prevalent and proteus mirabilis (P.M.) as an urease positive bacterium has frequently been reported. However, the epidemiological features and the association of this organism with urinary stone have not sufficiently been studied in Iran. This study was carried out to determine the prevalence of P.M. in patients with urinary stones who referred to the Urology Sections of Tehran and Zahedan Universities of Medical Sciences.
Materials & Methods: This case-control study was conducted on 300 urine samples from patients with urinary stones as study group and the same number of samples from subjects without urinary stones and infection as control group. All the samples were cultured on Mc Cankey and urinary PH was measured with pH paper. The data were analyzed statistically and odd's ratio was calculated.
Results: In 600 cultures, proteus mirabilis was detected in 14% of cases and in 3.3% of control group (P<0.0001 and O.R. 4.7). The number of the patients with pH>6 was five times more than those in control group.
Conclusion: Proteus mirabilis is an agent that causes alkaline urine and may enhance formation of stones. Further studies using prospective methods in order to overcome the problem are recommended.
Materials & Methods: This case-control study was conducted on 300 urine samples from patients with urinary stones as study group and the same number of samples from subjects without urinary stones and infection as control group. All the samples were cultured on Mc Cankey and urinary PH was measured with pH paper. The data were analyzed statistically and odd's ratio was calculated.
Results: In 600 cultures, proteus mirabilis was detected in 14% of cases and in 3.3% of control group (P<0.0001 and O.R. 4.7). The number of the patients with pH>6 was five times more than those in control group.
Conclusion: Proteus mirabilis is an agent that causes alkaline urine and may enhance formation of stones. Further studies using prospective methods in order to overcome the problem are recommended.
Type of Study: Original Research Article |
Received: 2008/11/10 | Accepted: 2002/03/15 | Published: 2002/03/15
Received: 2008/11/10 | Accepted: 2002/03/15 | Published: 2002/03/15
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