Background and Objectives: Stroke is the third leading cause of death in developed countries. It can also lead to a variety of neurological defects. Regarding the significance of rehabilitation in diminishing the complications, the present study was conducted to evaluate the effect of rehabilitation on life quality of patients suffering from stroke in Sahrekord in 2004.
Materials and Methods: This two-step quasi - experimental study (before and after) was carried out on 30 inpatients suffering from stroke who had been selected by simple sampling and were qualified to enter the research. The data were collected using the four - domain life quality questionnaire (physical - Mental- general health and social performance) before and after intervention. To analyse the data descriptive statistics (mean and standard deviation) and analytical statistics (Paired t-test, wilcoxon and independent t-test) were used.
Results: The results revealed that mean score of life quality in physical, mental, and social performance, and general health domains improved significantly following the rehabilitation measures (P=0.05). Moreover, the overall life quality increased significantly after rehabilitation compared to the period before (P=0.05).
Conclusion: Rehabilitation affects different aspects of life quality positively. Establishment and strengthening the rehabilitation, educational and supportive centers provides the patients with better access to these measures and might be a step forward to their independence.

Background and Objective: Chronic myeloid leukemia (CML) is a malignant clonal disorder of hematopoietic stem cells which results in increase of myeloid and erythroid cells and platelets in the peripheral blood and hyperplasia in bone marrow. This research evaluated the cytotoxic effect of aqueous, methanolic and ethanolic extracts of M. spicata leaves on K562 cell line as a model of chronic myeloid leukemia. Materials and Methods: In this experimental trial, leaves of M. spicata were collected from Booin city and extracted using soxhlet method. K562 cells were cultured and treated with concentrations of extracts (12.5-150μg/ml). Cytotoxicity of M. spicata extracts against K562 leukemia cells was estimated by the MTT test method. The absorbance was measured using ELISA plate reader at 540 nm. Results: Ethanolic extract showed the highest cytotoxic effect (IC50=75 μg/ml) whereas aqueous extract showed the least cytotoxic effect (IC50=150 μg/ml) among the extracts. Methanol extracts showed the cytotoxic effect with IC50=100 μg/ml on K562 cell line. Aqueous and alcoholic extracts exhibited a dose-dependent cytotoxic effect on K562 cell line. Conclusion: Considering the cytotoxic effects of aqueous and alcoholic extracts of M. spicata leaves on K562 cells, this plant can be considered as a potential candidate for further studies in the treatment of CML.