Background and Objective: Regarding high prevalence of musculoskeletal disorders (MSDs) among bakery workers and due to lack of information concerning posture analyzing, this study was carried out to identify working postures precisely in order to revise their work stations. Materials and Methods: In this cross-sectional study 334 Araki bakery workers were randomly selected. The data was collected using Nordic Musculoskeletal Questionnaire (NMQ) through interview and Ovako Working-posture Analysis System (OWAS) by video tapes. Based on OWAS postural analyzing, recommended actions based on different body regions for different jobs was separately introduced. Results: The averages of age and job experiences were 33±10.4 yr and 13.9±10 yr respectively. Most musculoskeletal disorders were in the knees (62.2%), low back (58.8%) and legs (53.9%) respectively. This research revealed that 42.2% of Araki bakery workers postures were in slightly up to very harmful postures. High prevalence of MSDs in different body regions caused 33.7% of workers to leave the work stations. Meanwhile awkward postures occurred in bent back (5.1%), twisted back (4.3%), bent and twisted back (2.8%) bent of knees (8.8%) and arms upper the shoulder (22.2%). The most awkward postures observed in job group of Shatters and there was a significant relation between neck, elbow, shoulder, knee disorders and work experiences (p<0/05). Conclusion: With regard to the results of this study, due to a high prevalence of musculoskeletal disorders and harmful postures (bending, rotation and combined postures with time prolonged percentage) in bakery workers, revision of work operation and use of appropriate equipments in these jobs seems imperative. Therefore, an ergonomic intervention in order to correct poor postures is suggested.

Background and Objective: Breast tumors include the heterogeneous population of various cells such as luminal and myoepithelial cells which can play a significant role in the development and/or the inhibition of breast cancer. It has been observed that paracrine and autocrine activities of myoepithelial cells can limit the mammary tumors via angiogenesis inhibition and apoptosis induction. Therefore, the present study was set to isolate mice mammary myoepithelial cells and to assess their cell death-inducing potential in the breast carcinogenic cells.

Materials and Methods: In this experimental study following the primary culture of mice-isolated myoepithelial cells, specific marker of the myoepithelial cells was determined by flow cytometry analysis. Then, myoepithelial cells were co-cultured with breast carcinoma cells, and the viability of cells was assayed by MTT on the 1st, 3rd, and 5th days after co-culture.

Results: The isolated cells were spindle shaped and elongated. Flow cytometric analysis showed cells with myoepithelial marker including CD10 expression. The co-culture results elicited that the myoepithelial cells significantly inhibited the proliferation and the growth of breast carcinoma cells on the 1st, 3rd, and 5th days after co-culture (P<0.05).

Conclusion: Implementation of myoepithelial cells in the inhibition of mammary cancerous cells is postulated as a new and an efficient approach for cancer therapy.