Background and Objective: The duodenum is the second most commonly occurring diverticulum in the gastrointestinal tract. Though, the diverticulum can induce various complications, no logical screening has been provided for them so far. In this study, the relative prevalence of duodenal diverticulum and their association with bile ducts in patients with pancreatic biliary disease were studied.
Materials and Methods: This cross-sectional study was performed on 310 patients who underwent ERCP for various reasons. The presence or absence of duodenal diverticulum and complications were also evaluated.
Results: Of 310 patients, 62 (20%) had duodenal diverticulum and the frequency of diverticulum in the order of prevalence was: type B (39%), type D (26%), type A (21%) and type C (14%). The prevalence of the biliary stones in diverticulum group was significantly higher. The biliary duct stenosis was lower in the group with diverticulum and the mean age was significantly higher. There was no significant difference between the two sexes.
Conclusion: The results of this study showed that the prevalence of duodenal diverticulum in patients who underwent ERCP in gasteroenterology and Hepatology Diseases Center of Qom University of Medical Sciences was higher than the previous studies. There was a significant difference in the incidence of duodenal diverticulum among different age groups. It seems that the diverticulum increase the risk of biliary stones and reduce bile duct stenosis.

Cytomegalovirus is a type of herpes viruses which can cause a primary infection or reactivate after a latent period. It can involve all organs including the gastrointestinal system. The most common presentation of GI involvement is colitis.
In this report, we describe a middle-aged woman presenting with diarrhea, ascites, and edema in both upper and lower extremities.  She had no history of immunodeficiency or use of immunomodulators. Colonoscopic and pathologic findings revealed CMV colitis leading to protein-losing enteropathy.
CMV colitis, though rare in immunocompetent patients, should be considered in the differential diagnosis of diarrhea and abdominal pain.

Case presentation: A 32-year-old man with dyspepsia and rectorrhagia dating back 3 weeks underwent endoscopy and colonoscopy. Upper GI endoscopy revealed a 2×2cm submucosal lesion at the gastric body. Endoscopic ultrasonography confirmed GIST and surgery was recommended. Colonoscopy diagnosed left side inflammatory bowel disease (IBD) (ulcerative colitis). Abdominal CT scan and sonography had no apparent abnormality. The pathology report confirmed low grade, spindle type gastrointestinal stromal tumor (GIST). Treatment was started with oral Mesalazine and Asacol enema. As the abdominal and pelvic CT showed no metastasis, a complete surgical resection of the tumor was performed and in a 6-month follow up, the patient had no problem.
Discussion: IBD patients are at an increased risk of malignancy due to chronic inflammatory state and the use of immunomodulator agents. Thus, the risk of malignancies at the beginning of the disease is low and its occurrence is rare.  The most common cancer in such patients is adenocarcinoma and GIST is somehow rare, with a small number reported in literature. Since the presence of GIST is not related to disease activity, it should be considered in differential diagnosis in patients with controlled IBD who are still symptomatic.