Showing 7 results for عریان
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Volume 5, Issue 18 (3-1997)
Abstract
Oryan.s , Rahnama.m,
Volume 5, Issue 21 (12-1997)
Abstract
Shirvani, A., Parivar, K., Riazi, Gh., Oryan, Sh,
Volume 6, Issue 23 (6-1998)
Abstract
Rahnema, M., , ,
Volume 6, Issue 25 (12-1998)
Abstract
Habibollah Johari, Shahrbano Oryan, Kazem Parivar, Ali Haeri Rouhani, Nader Tanide,
Volume 10, Issue 38 (3-2002)
Abstract
Background: Chronic renal failure leads to several functional disturbances in the regulation of body fluid composition, excretion, and metabolism which is known as uremic syndrome. There are reports of chronic renal disturbances following adenine containing food regimens in animals. In this study, the effect of intraperitoneal injection of soluble adenine on chemical composition of serum and urine osmolality was investigated.
Materials and Methods: In this experimental study different concentrations of soluble adenine were injected to Sprague-Dawly rats from days 2 to 16 after birth. Factors such as serum and urine osmolality, urine volume and serum chemical factors such as glucose, urea, creatinine, sodium, potassium and body weight were measured after the injection of adenine up to 140 days.
Results: Serum osmolality, urea and creatinine increased after adenine injections, while body weight, urine osmolality and urine volume decreased. Meanwhile, the concentration of serum glucose, sodium and potassium did not show any significant changes.
Conclusion: Adenine induces an imbalance in many chemical factors of serum in chronic renal failure. Further studies on the effect of adenine reduction in diet on uremic syndrome are recommended.
Mehrdad Shariati, Kazem Parivar, Shahrbano Oryan, Abbas Shokravi, Robabeh Alizadeh,
Volume 11, Issue 42 (Mar 2003)
Abstract
Background: Due to the problems arising from the overpopulation, attention has been focused on contraceptives for men. Phenanthrolines are a group of organic compounds with ionophilic characteristics and a wide range of use in biology and chemistry. In this study the effect of 2,6-diaminopyridinum was studied on hypophysis-gonad axis, testicular tissue and sperm production in male Balb/c mice.
Materials and Methods: Fifty adult male Balb/C mice were divided in 5 groups. First group was used as untreated control. Saline was injected to the 2nd group and the remaining 3 groups were received intraperitoneal injection of 15, 20 and 25 mg/kg of 2,6-diaminopyridinum every other day for 20 days. The LD50 was determined to be 35 mg/kg body weight. The serum concentrations of FSH, LH and testosterone were measured and the testicular tissues were studied morphologically.
Results: The data showed that 25 mg/kg diaminopyridinum decreased the serum testosterone level significantly with no changes on FSH and LH levels. Histological studies on testicular tissue showed a significantly lower numbers of germ cells.
Conclusion: The data obtained in this study indicate that 25 mg/kg of phenanthroline may directly affect testicular tissue causing a lower testosterone level and spermatogenesis in mice.
Majid Aghdasi, Shahrbanoo Oryan, Kazem Parivar,
Volume 15, Issue 58 (3-2007)
Abstract
Background & objective: With regard to increasing use of opioids and their potential role in infertility research centers around the world are in search of pharmacologic compounds which could neutralize effects of opioids and overcome infertility through administration of GnRH and its analogues which also do not have considerable side effects.
Materials & Methods: In this study male wistar rats weighing 200-250 gr were used. At different intervals (5-10-15 days) 5mg/kg morphine was injected intraperitonneally into the male rats. Then they were divided in 5 groups of 8. The first group contained intact rats, while saline, morphine, naloxone, and fertagyl were injected into the second third, fourth and fifth groups respectively. Then the rats were anesthetized and their bloods were taken for further tests.
Results: The results showed that morphine induces loss of testis weight and diameter, loss of weight in rats, and nutritional and behavior changes. Furthermore, a significant changes in the amounts of LH and testosterone hormones was observed in all groups (p<0.05) while no significant change in the amount of FSH was observed.
Conclusion: Since the experimental groups into which naloxone and GnRH were injected showed no significant difference, we suggest that naloxone and GnRH be administrated as opioid antagonist to slove the problem of morphine-induced infertility.
