Background and Objective: HG is a severe form of expectancy nausea and vomiting, occurring in 0/5 to 2% of the expectancies. The etiology of HG is unknown, though hormonal stimuli, and psychologic predisposition are attributable to the condition. Recent studies suggest a relationship between HG and H.pylori infection. The aim of this study was to investigate the  relationship between HG and H.pylori infection.
Material and Methods: Forty pregnant women with HG (Treatment group) and forty asymptomatic pregnant women (control group) were assigned into the research from April  to August 2006. Specific serum immunoglobulin G (IgG) for H.pylori was assayed by ELISA. The data was analyzed using SPSS software, Chi-Square and T-test.
Results: Out of 40 pregnant women with HG 25 individuals (62/5%) were found to have serologically positive H.pylori, whereas in asymptomatic pregnant women 19 (47.5%) individuals were positive, which shows no significant difference between H.Pylori infection with HG (P=0.178). No significant difference was observed between positive H.pylori and the number of pregnancy, body mass index (BMI), and duration of  hospital stay.
Conclusion: Since HG has a multifactorial etiology and with regard to high prevalenve of H pylori in our country, research studies with higher sample sizes and utilization of more sensitive diagnostic methods for the detection of active H pylori is recommended.

Background and Objective: Striae Gravidarum found during pregnancy may be an indicative of poor skin elasticity and may prone to tearing perineal and vaginal tissues during vaginal delivery. The aim of this study was to determine relationship between striae gravidarum and perineal trauma and vaginal lacerations in women referred to Hajar Hospital Labor Ward in Shahr-e kord city. Materials and Methods: This cross-sectional study included 587 women who referred to Hajar Hospital Labor Ward for vaginal delivery in 2010-2011. The study was conducted within the first and second stages of labor. Data was collected by using interviews, hospital files and physical examinations. Descriptive statistics and chi square test, t- student test, one-way ANOVA and step-wise multivariate logistic regression were used to analyze the collected data. Results: 82.8 percent of the participants developed stretch marks.14.5 percent of the pregnant women in this study experienced vaginal and perineal tears. There was a significant association of vaginal and perineal tears with conduction anesthesia (P<0.0001), vaginal dilation (P=0.023), duration of the first stage (p=0.044), and breast striae gravidarum score (P=0.005). No significant association was found between vaginal and perineal tears and neonatal birth weight, head circumference and maternal BMI (P>0.05). Conclusion: Patients with breast striae gravidarum are at a higher risk of vaginal and perineal lacerations at the time of vaginal delivery. This finding suggests that midwives and obstetricians consider beast striae gravidarum score as a simple and non- invasive tool for assessment of vaginal and perineal lacerations in management of women during vaginal delivery.

Background and Objective: Gestational trophoblastic disease (GTD) is a type of disease which is characterized by increased production of B-HCG by placental cells. Increased β-HCG production is due to increased proliferation of beta cells and lack of apoptosis. If left untreated, it can lead to malignancy. Almost 30-50 of GTD progresses to gestational trophoblastic neoplasia (GTN) in women over 40 years old. This study aimed to evaluate the effect of vitamin A doses (100,000 IU and 200,000 IU) on the decrement of β-HCG levels.
Materials and Methods: The study included three groups: two patients and one control, and each group contained 22 individuals. Two groups of patients (A and B) received 100,000 IU and 200,000 IU doses of vitamin A, respectively, in addition to suction curettage. β-HCG levels were then measured by radioimmunoassay (RIA).
Results: The β-HCG drop-in group B, which received 200,000 IU of vitamin A, was higher than that of group A. It was significant in the third and fourth weeks after the treatment compared to the control group. There was also a significant relationship between the three groups in terms of Gravid (P<0.001). All the patients were followed up for 6 months.
Conclusion: Considering that in the long run, the dose of 200,000 IU compared to the dose of 100,000 IU of vitamin A did not significantly reduce the B-HCG, therefore, in order to prevent the complications of high doses, the single dose of 100,000 IU was used for GTD patients.