Volume 9, Issue 36 (9-2001)                   J Adv Med Biomed Res 2001, 9(36): 27-31 | Back to browse issues page

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Mellati A O, Mousavinasab N. Study Of Serums Alt And Ast In Positive Hbsag Blood Donors Referring To The Blood Transfusion Organization In Zanjan. J Adv Med Biomed Res 2001; 9 (36) :27-31
URL: http://journal.zums.ac.ir/article-1-435-en.html
Abstract:   (154410 Views)
It has been known that hepatitis B surface antigen (HBsAg) is the first detectable evidence of infection with hepatitis B appearing in serum within 1 to 10 weeks of exposure and 2 to 6 weeks perior to the onset of clinical symptoms. Various studies have reported the relative frequency of hepatitis B patients differently in relation with transaminase increase, moreover, some of the other writers have reported that hepatitis B viral infection dose not cause significant serum transaminase increase in patients. In this study, among 90 cases, 15 people (17.6%) were observed to be with ALT elevation, and 17 people (19%) with AST elevation. Because of low percentage of HBsAg blood donors with transaminase level elevation, it is not possible to consider these enzymes as a wide and sensitive marker of viral hepatitis diagnosis. Also, the difference in age and sex does not have any significant effect on transaminase increase.
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Type of Study: Original Research Article |
Received: 2008/11/10 | Accepted: 2001/09/15 | Published: 2001/09/15

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