It has been known that hepatitis B surface antigen (HBsAg) is the first detectable evidence of infection with hepatitis B appearing in serum within 1 to 10 weeks of exposure and 2 to 6 weeks perior to the onset of clinical symptoms. Various studies have reported the relative frequency of hepatitis B patients differently in relation with transaminase increase, moreover, some of the other writers have reported that hepatitis B viral infection dose not cause significant serum transaminase increase in patients. In this study, among 90 cases, 15 people (17.6%) were observed to be with ALT elevation, and 17 people (19%) with AST elevation. Because of low percentage of HBsAg blood donors with transaminase level elevation, it is not possible to consider these enzymes as a wide and sensitive marker of viral hepatitis diagnosis. Also, the difference in age and sex does not have any significant effect on transaminase increase.
Type of Study:
Original Research Article |
Received: 2008/11/10 | Accepted: 2001/09/15 | Published: 2001/09/15