Volume 26, Issue 117 (9-2018)                   J Adv Med Biomed Res 2018, 26(117): 1-11 | Back to browse issues page

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Molaei B, Fallah R, Kazemi A, Rashtchi V, Soltani S. Comparison of the Effect of Diclofenac Suppository and Intravenous Paracetamol on Post Cesarean Pain and Bleeding. J Adv Med Biomed Res 2018; 26 (117) :1-11
URL: http://journal.zums.ac.ir/article-1-5399-en.html
Comparison of the Effect of Diclofenac Suppository and Intravenous Paracetamol on Post Cesarean Pain and Bleeding
Behnaz Molaei1 , Ramezan Fallah2 , Atefeh Kazemi1 , Vahideh Rashtchi * 3, Sahar Soltani4
1- Dept.of Obstetrics and Gynecology, Faculty of Medicine,Zanjan University of Medical Sciences, Zanjan, Iran
2- Dept.of Biostatistics, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
3- Dept.of Anesthesiology, Faculty of Nursing and Midwifery, Zanjan University of Medical Sciences, Zanjan, Iran
4- Zanjan University of Medical Sciences, Zanjan, Iran
Abstract:   (151390 Views)

Background and Objective: The cesarean section is one of the most common surgical procedures performed today. Two common complications are pain and bleeding which, if incorrectly controlled, may develop into increased complications. The aim of this research was to compare the effects of diclofenac suppository and intravenous paracetamol on post-cesarean pain and bleeding.
Methods and Materials: In this clinical trial, 88 patients (ASA class I and II, 15-45 years old) who underwent elective cesarean under spinal anesthesia were randomly divided into two groups.In the first group,100 mg diclofenac suppository was administered and in the second group 1g IV paracetamol in 100 ML normal saline was administered immediately after transfer to recovery section and repeated every 6 hours for 24 hours. Pain assessment was done by Visual Analogue Scale (VAS) before intervention and after 6, 12, 18 and 24 hours. The control of postpartum hemorrhage was assessed by clinical examination, measurement of Hemoglobin 6 and 12 hours after surgery and Pad Score. Data were analyzed by repeated measures and independent t-test via SPSS 16.
Results: The mean score of pain and severe bleeding in the paracetamol group was significantly lower than in the diclofenac group (p<0.05).
Conclusion: According to the results of this study, intravenous paracetamol is more effective than diclofenac suppository in controlling post-cesarean pain and bleeding.

Keywords: Pain, Bleeding, Cesarean, Paracetamol, Diclofenac
Full-Text [PDF 2625 kb]   (158560 Downloads)    
Type of Study: Original Article |
Received: 2018/11/10 | Accepted: 2018/11/10 | Published: 2018/11/10
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