Volume 31, Issue 145 (March & April 2023)                   J Adv Med Biomed Res 2023, 31(145): 158-169 | Back to browse issues page

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Dolatkhah N, Toopchizadeh V, Farshbaf Khalili A, Emamizad S, Salekzamani Y, Taleschian Tabrizi N et al . Correlation of Dietary Protein Intake with Body Composition and Physical Status in Patients with Knee Osteoarthritis. J Adv Med Biomed Res 2023; 31 (145) :158-169
URL: http://journal.zums.ac.ir/article-1-6371-en.html
Correlation of Dietary Protein Intake with Body Composition and Physical Status in Patients with Knee Osteoarthritis
Neda Dolatkhah * 1, Vahideh Toopchizadeh2 , Azizeh Farshbaf Khalili2 , Sanaz Emamizad3 , Yaghoub Salekzamani2 , Negar Taleschian Tabrizi3 , Maryam Hashemian4
1- Physical Medicine and Rehabilitation Research Center, Tabriz University of Medical Sciences, Tabriz, Iran , neda_dolatkhah@yahoo.com
2- Physical Medicine and Rehabilitation Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
3- Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
4- Dept. of Biology, School of Arts and Sciences, Utica College, Utica, United States of America
Abstract:   (11080 Views)

Background and Objective: Little is known about the association between dietary protein intake and clinical manifestations in osteoarthritis (OA) patients. We aimed to determine the correlation between dietary protein intake and pain severity, functional status, and body composition indices in patients with knee OA.
Materials and Methods: This cross-sectional study was performed on 220 OA patients, staged I to Ⅲon Kellgren and Lawrence scale. Patients were selected randomly via cluster sampling method from the health centers of Tabriz between October 2017 and October 2018. We estimated the participants' protein intakes using a semi-quantitative food frequency questionnaire. Western Ontario and McMaster Index (WOMAC) was used to measure the functional status. We used the Visual Analogue Scale to measure pain severity. A bioelectric impedance device measured the patients’ body composition.
Results: Total dietary protein intake was 55.36±24.14 grams per day. Higher dietary total and animal-based protein intakes were associated with lower pain severity. There were reverse correlations between dietary protein intakes (total and animal-based) with the physical disability according to WOMAC total, WOMAC pain, and WOMAC stiffness scores in the subset of patients who didn’t meet the 75 percent of recommended dietary allowance. In these patients, higher total, plant-based, and animal-based protein intakes correlated with WOMAC functional scores. Higher total and animal-based protein intakes were associated with higher soft lean and lean body mass in women.
Conclusion: Dietary protein intake needs to improve in knee OA patients, and dietary protein intake might be an intermediation objective in these patients.

Keywords: Body composition, Dietary protein, Functional status, Knee osteoarthritis, Pain
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✅Dietary protein intake needs to improve in knee OA patients, and dietary protein intake might be an intermediation objective in these patients.


Type of Study: Original Article | Subject: Clinical medicine
Received: 2021/01/13 | Accepted: 2022/09/23 | Published: 2023/03/13
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