Volume 31, Issue 144 (January & February 2023)                   J Adv Med Biomed Res 2023, 31(144): 40-45 | Back to browse issues page


XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mehdizadeh H, Bahari Z, Zekriamir S, Shahriary H, Behzadnia M J. The Aassociation between Pre-Cardiac Arrest Comorbidity and Unsuccessful Cardiopulmonary Resuscitation in Patients with Cardiac Arrest. J Adv Med Biomed Res 2023; 31 (144) :40-45
URL: http://journal.zums.ac.ir/article-1-6735-en.html
1- Student Research Committee, Baqiyatallah University of Medical Sciences, Tehran, Iran
2- Dept. of Physiology and Medical Physics, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran
3- Trauma Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran , behzadnia@bmsu.ac.ir
Abstract:   (11022 Views)

Background and Objective: Patients suffering from cardiac arrest (CA) have poor prognosis and survival. The association of pre-arrest comorbidity with unsuccessful resuscitation in patients with CA is far from clear. The aim of the present study was to investigate the association between pre-existing comorbidity and unsuccessful resuscitation following CA in Iranian patients.
Materials and Methods: Data of all the patients with CA (1320 patients) who were admitted to Baqiyatallah Hospital (Tehran, Iran), and underwent cardiopulmonary resuscitation (CPR) from 2018 to 2020 were retrospectively reviewed. We analyzed the association of comorbidity data with the mortality rate and unsuccessful CPR.
Results: In the present study, 794 (60.2%) patients were female. Most CAs occurred in the hospital (1289). The case fatality rate (CFR) of CA was 69.92%. Additionally, of the 1320 patients, CPR was unsuccessful in 1271 (96.3%) patients. Our data analysis revealed that gender had no significant relationship with the mortality rate and unsuccessful CPR. However, age was significantly associated with mortality, but not with unsuccessful CPR. CA, respiratory distress, and impaired consciousness were significantly associated with mortality. Furthermore, cardiomyopathy, coronary artery bypass grafting (CABG), renal disease (P=0.032), and poisoning had a significant correlation with mortality. In addition, CABG and congestive heart failure (CHF) were significantly correlated with the unsuccessful CPR.
Conclusion: The present study suggested that CABG and CHF had a significant relationship with unsuccessful resuscitation. Furthermore, cardiomyopathy, CABG, renal disease, and poisoning were significantly associated with mortality.

Full-Text [PDF 437 kb]   (10405 Downloads) |   |   Full-Text (HTML)  (888 Views)  

The present study suggested that CABG and CHF had a significant relationship with unsuccessful resuscitation. Furthermore, cardiomyopathy, CABG, renal disease, and poisoning were significantly associated with mortality.


Type of Study: Original Research Article | Subject: Clinical Medicine
Received: 2021/09/28 | Accepted: 2022/07/26 | Published: 2022/12/12

References
1. Andrewa E, Nehmea Z, Bernard S, Smith K. The influence of comorbidity on survival and long-term outcomes after out-of-hospital cardiac arrest. Resuscitation. 2017; 110:42-7. [DOI:10.1016/j.resuscitation.2016.10.018] [PMID]
2. Reis C, Akyol O, Araujo C,et al. Pathophysiology and the monitoring methods for cardiac arrest associated brain injury. Int J Mol Sci. 2017; 18:129. [DOI:10.3390/ijms18010129] [PMID] [PMCID]
3. Koldobskiy D, Groves S, Scharf SM, Cowan MJ. Validation of factors affecting the outcome of cardiopulmonary arrest in a large, urban, academic medical center. Crit Care Med. 2014; 2014:168132. [DOI:10.1155/2014/168132]
4. Hirlekar G, Jonsson M, Karlsson T, Hollenberg J, Albertsson P, Herlitz J. Comorbidity and survival in out-of-hospital cardiac arrest. Resuscitation. 2018; 133:118-23. [DOI:10.1016/j.resuscitation.2018.10.006] [PMID]
5. Nolan JP, Laver SR, Welch CA, Harrison DA, Gupta V, Rowan K. Outcome following admission to UK intensive care units after cardiac arrest: a secondary analysis of the ICNARC Case Mix Programme Database. Anaesthesia. 2007; 62:1207-16. [DOI:10.1111/j.1365-2044.2007.05232.x] [PMID]
6. Herlitz J, Bång A, Gunnarsson J,et al. Factors associated with survival to hospital discharge among patients hospitalised alive after out of hospital cardiac arrest: change in outcome over 20 years in the community of G€oteborg, Sweden. Heart. 2003; 89:25-30. [DOI:10.1136/heart.89.1.25] [PMID] [PMCID]
7. qbal MB, Al-Hussaini A, Rosser G, et al.Predictors of survival and favorable functional outcomes after an out-of-hospital cardiac arrest in patients systematically brought to a dedicated heart attack center (from the Harefield cardiac arrest study). Am J Cardiol. 2015; 115:730-7. [DOI:10.1016/j.amjcard.2014.12.033] [PMID]
8. Winther-Jensen M, Kjaergaard J, Nielsen N, et al.Comorbidity burden is not associated with higher mortality after out-of-hospital cardiac arrest. Scand Cardiovasc J. 2016; 50:305-10. [DOI:10.1080/14017431.2016.1210212] [PMID]
9. Beesems SG, Blom MT, van der Pas MH,et al. Comorbidity and favorable neurologic outcome after out-of-hospital cardiac arrest in patients of 70 years and older. Resuscitation. 2015; 94:33-9. [DOI:10.1016/j.resuscitation.2015.06.017] [PMID]
10. Wyckoff MH, Singletary EM, Soar J,et al. 2021 international consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations: summary from the basic life support; advanced life support; neonatal life support; education, implementation, and teams; first aid task forces; and the COVID-19 Working group. Circulation. 2022; 145(9):645-721. [DOI:10.1161/CIR.0000000000001017] [PMID]
11. Nayeri A, Bhatia N, Holmes B,et al. Pre-existing medical comorbidity is not associated with neurological outcomes in patients undergoing targeted temperature management following cardiac arrest. Heart Vessels. 2017; 32(11):1358-63. [DOI:10.1007/s00380-017-1005-4] [PMID]
12. Søholm H, Hassager C, Lippert F,et al. Factors associated with successful resuscitation after out-of-hospital cardiac arrest and temporal trends in survival and comorbidity. Ann Emerg Med. 2015; 65(5):523-31. [DOI:10.1016/j.annemergmed.2014.12.009] [PMID]
13. Hirlekar G, Jonsson M, Karlsson T, Hollenberg J, Albertsson P, Herlitz J. Comorbidity and survival in out-of-hospital cardiac arrest. Resuscitation 2018; 133:118-23. [DOI:10.1016/j.resuscitation.2018.10.006] [PMID]
14. Arnett DK, Goodman RA, Halperin JL, Anderson JL, Parekh AK, Zoghbi WA. AHA/ACC/HHS strategies to enhance application of clinical practice guidelines in patients with cardiovascular disease and comorbid conditions: from the American Heart Association, American College of Cardiology, and US Department of Health and Human Services. Circulation. 2014; 130(18):1662-7. [DOI:10.1161/CIR.0000000000000128] [PMID]

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2025 CC BY-NC 4.0 | Journal of Advances in Medical and Biomedical Research

Designed & Developed by : Yektaweb