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Kamel S, Mehrabani S, Esmaeili M, hajiahmadi M H, karimnezhad M. Comparison of a Clear Liquid Diet Versus a Low-Fiber Diet Regimen in Pediatric Colonoscopy: A Randomized Clinical Trial. J Adv Med Biomed Res 2024; 32 (150) :60-66
URL: http://journal.zums.ac.ir/article-1-7313-en.html
Comparison of a Clear Liquid Diet Versus a Low-Fiber Diet Regimen in Pediatric Colonoscopy: A Randomized Clinical Trial
Setareh Kamel * 1, Sanaz Mehrabani2 , Mohammadreza Esmaeili3 , Mahmood Haji Hajiahmadi4 , Maryam Karimnezhad4
1- Student Research Committee, Babol University of Medical Sciences, Babol, Iran , setarehkamell@gmail.com
2- Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
3- Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR Iran
4- Clinical Research Development Unit of Amirkola Children’s Hospital, Babol University of Medical Sciences, Babol, Iran
Abstract:   (201 Views)

Background & Objective: Colonoscopy serves as a diagnostic and therapeutic tool for children. However, the process of bowel preparation presents a considerable challenge. This study aimed to compare the effectiveness of a clear liquid diet (CLD) versus a low-residue diet (LRD) in bowel preparation for colonoscopy among children aged 2-14 years.
Materials & Methods: In this single-blind clinical trial, a total of 110 children aged 2-14 years undergoing colonoscopy were randomly assigned to two groups: the CLD group and the LRD group. Along with their assigned diets, all participants received 2 g/kg of polyethylene glycol in two or three divided doses, as well as a single dose of 5-mg bisacodyl prior to colonoscopy. The primary outcome was the adequacy of bowel cleansing for colonoscopy, evaluated using the Boston Bowel Preparation Scale (BBPS) in both groups. The secondary outcomes included the tolerability of bowel preparation diets and adverse effects.
Results: According to the physician’s assessment, the CLD group had favorable BBPS scores (BBPS ≥5) in 96.5% (55/57) of cases, while the LRD group had favorable scores in 98.1% (52/53) of cases. There were no significant differences between the two groups in terms of the mean BBPS score, regimen tolerability, and adverse effects. 
Conclusion: This study demonstrated that both CLD and LRD regimens were effective in bowel preparation and were well-tolerated by children aged 2-14 years.

Keywords: Low-fiber diet, Clear liquid diet, Colon cleansing, Colonoscopy, Children
Full-Text [PDF 584 kb]   (105 Downloads)    
Type of Study: Original Article | Subject: Clinical medicine
Received: 2023/08/8 | Accepted: 2023/11/20 | Published: 2024/01/30
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