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Volume 33, Issue 157 (March & April 2025)
J Adv Med Biomed Res 2025, 33(157): 7-7 |
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Ethics code: IR.ZUMS.REC.1403.002
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Jafari S, Mansori K, Barhgi F, Sheikhi M, Salehi M. The Ratio of Red Blood Cell Distribution Width to Serum Calcium Level in Predicting the Severity of Acute Pancreatitis. J Adv Med Biomed Res 2025; 33 (157) :7-7
URL: http://journal.zums.ac.ir/article-1-7636-en.html
URL: http://journal.zums.ac.ir/article-1-7636-en.html
1- Zanjan University of Medical Sciences
2- Zanjan University of Medical Sciences ,mohsen_salehi44@yahoo.com
2- Zanjan University of Medical Sciences ,
Abstract: (18 Views)
Background & Objective: The present study was designed to investigate the ratio of red blood cell distribution width (RDW) to serum calcium level in predicting the severity of acute pancreatitis.
Materials and Methods: In this cross-sectional study, 336 patients with acute pancreatitis referred to the emergency room of Valiasr and Mousavi hospitals were investigated during 2022-2023. The data collection tool was a checklist including demographic, clinical and laboratory variables that were extracted from the patient records. The data were analyzed using STATA16 and the area under the ROC curve was used to determine the best cut off point for the ratio of RDW to serum calcium level.
Results: 188 had mild pancreatitis and 148 had moderate/severe pancreatitis. The mean age of patients with mild and moderate/severe acute pancreatitis were 60.22 (±17.84) and 58.68 (±18.53) years, respectively. The frequency of women in mild and moderate/severe pancreatitis was 53.2% and 52%, respectively. The multiple logistic regression model showed that for every one unit increase in the mean RDW to Calcium ratio, the odds of developing moderate/severe pancreatitis increased 4.30-fold (OR= 4.30 – P<0.001). The best cutoff for the ratio of RDW to serum calcium in predicting moderate/severe acute pancreatitis was 1.69. The sensitivity, specificity, positive predictive value, negative predictive value, and area under the ROC curve for this cutoff were 83.45%, 85.47%, 85.17%, 83.77%, and 0.8698, respectively.
Conclusion: The ratio of RDW to serum calcium can be a rapid, available, inexpensive, sensitive, and reliable indicator for predicting the severity of acute pancreatitis.
Materials and Methods: In this cross-sectional study, 336 patients with acute pancreatitis referred to the emergency room of Valiasr and Mousavi hospitals were investigated during 2022-2023. The data collection tool was a checklist including demographic, clinical and laboratory variables that were extracted from the patient records. The data were analyzed using STATA16 and the area under the ROC curve was used to determine the best cut off point for the ratio of RDW to serum calcium level.
Results: 188 had mild pancreatitis and 148 had moderate/severe pancreatitis. The mean age of patients with mild and moderate/severe acute pancreatitis were 60.22 (±17.84) and 58.68 (±18.53) years, respectively. The frequency of women in mild and moderate/severe pancreatitis was 53.2% and 52%, respectively. The multiple logistic regression model showed that for every one unit increase in the mean RDW to Calcium ratio, the odds of developing moderate/severe pancreatitis increased 4.30-fold (OR= 4.30 – P<0.001). The best cutoff for the ratio of RDW to serum calcium in predicting moderate/severe acute pancreatitis was 1.69. The sensitivity, specificity, positive predictive value, negative predictive value, and area under the ROC curve for this cutoff were 83.45%, 85.47%, 85.17%, 83.77%, and 0.8698, respectively.
Conclusion: The ratio of RDW to serum calcium can be a rapid, available, inexpensive, sensitive, and reliable indicator for predicting the severity of acute pancreatitis.
Type of Study: Original Research Article |
Subject:
Clinical Medicine
Received: 2025/01/15 | Accepted: 2025/05/10 | Published: 2025/05/29
Received: 2025/01/15 | Accepted: 2025/05/10 | Published: 2025/05/29
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