Fri, Jun 27, 2025
[Archive]
Volume 33, Issue 157 (March & April 2025)
J Adv Med Biomed Res 2025, 33(157): 146-152 |
Back to browse issues page
Ethics code: IR.ZUMS.REC.1402.280
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Mohamadkhani M, Rozeh M E, Jouybari R M, Ladan A H, Ahmadi F. The Prevalence of Mesenteric Adenitis Among Children with Intussusception: A Cross-sectional Study. J Adv Med Biomed Res 2025; 33 (157) :146-152
URL: http://journal.zums.ac.ir/article-1-7643-en.html
URL: http://journal.zums.ac.ir/article-1-7643-en.html
Mohadeseh Mohamadkhani1 
, Mohammad Esagh Rozeh *2 
, Reza Mahdian Jouybari1 , Amir Hossein Ladan1 , Farzane Ahmadi3
, Mohammad Esagh Rozeh *2 , Reza Mahdian Jouybari1 , Amir Hossein Ladan1 , Farzane Ahmadi3
1- Department of Pediatrics, School of Medicine, Ayatollah Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran
2- Department of Pediatrics, School of Medicine, Ayatollah Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran ,dr.rozeh@zums.ac.ir
3- Department of Epidemiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
2- Department of Pediatrics, School of Medicine, Ayatollah Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran ,
3- Department of Epidemiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
Abstract: (194 Views)
Background and Aims: Intussusception is the most common abdominal emergency in children. The present study was designed to investigate the prevalence of mesenteric adenitis among children with intussusception.
Methods: This cross-sectional study was conducted on 81 children aged 4 to 48 months with intussusception who were referred to Mousavi Zanjan Hospital during 2019-2021. Data were collected using a checklist including demographic and clinical variables extracted from the patients' records. The data were analyzed using SPSS software, version 26.
Results: The mean±SD age of the participants was 22.30±13.56 months. Most children were girls (70.4%). Ileocolic (45.8%) was the most common type of intussusception, and most children had mesenteric adenitis (79%). In terms of number, most (93.7%) cases of adenitis were multiple, and the right lower quadrant (RLQ) was the most common site of adenitis (85.9%). Moreover, 56.2% of adenitis had a diameter of less than 1 cm. No statistically significant associations were observed between mesenteric adenitis and variables such as age, sex, weight, time of onset of symptoms, duration of hospitalization, vomiting, type of intussusception, type of nutrition, type of treatment, and type of delivery (P>0.05). However, there was a statistically significant relationship between jelly stool and mesenteric adenitis, so all children with jelly stool had mesenteric adenitis (P=0.009).
Conclusion: The prevalence of mesenteric adenitis was high in children with intussusception, and a significant association was observed between these two diseases. However, further studies with larger sample sizes are recommended.
Type of Study: Original Research Article |
Subject:
Clinical Medicine
Received: 2025/01/22 | Accepted: 2025/05/12 | Published: 2025/05/29
Received: 2025/01/22 | Accepted: 2025/05/12 | Published: 2025/05/29
References
1. Abantanga FA, Hesse AA, Lakhoo K. Intussusception. Pediatric Surgery: A Comprehensive Textbook for Africa. 2020. pp. 705-18. [DOI:10.1007/978-3-030-41724-6_68]
2. Kopystecka A, Kopeć I, Mitek-Palusińska J, Woźniak MM. Intestinal intussusceptions in children population. J Educ Health Sport. 2022;12(8):1176-89. [DOI:10.12775/JEHS.2022.12.08.102]
3. Fiordaliso M, Panaccio P, Costantini R, De Marco AF. Comparison between children and adults intussusception. Description of two cases and review of literature. Ann Ital Chir. 2021;92(3):268-76.
4. Shinde N, Veerendra M. Clinical Manifestations and Management of Intussusception in Children. RGUHS J Med Sci. 2019;9(4):150-7. [DOI:10.26463/rjms.9_4_2] [PMID]
5. Hwang S, Kim J, Jung JY, Ham EM, Park JW, Kwon H, et al. The epidemiology of childhood intussusception in South Korea: an observational study. Plos One. 2019;14(12):e0219286. [DOI:10.1371/journal.pone.0219286] [PMID] [PMCID]
6. Bradshaw CJ, Johnson P. Intussusception. Surgery (Oxford). 2022;40(5):311-5. [DOI:10.1016/j.mpsur.2022.03.001]
7. Guo W-l, Geng J, Zhan Y, Tan Y-l, Hu Z-c, Pan P, et al. Forecasting and predicting intussusception in children younger than 48 months in Suzhou using a seasonal autoregressive integrated moving average model. BMJ Open. 2019;9(1):e024712. [DOI:10.1136/bmjopen-2018-024712] [PMID] [PMCID]
8. Kelley-Quon LI, Arthur LG, Williams RF, Goldin AB, Peter SDS, Beres AL, et al. Management of intussusception in children: a systematic review. J Pediatr Surg. 2021;56(3):587-96. [DOI:10.1016/j.jpedsurg.2020.09.055] [PMID] [PMCID]
9. Bines JE, At Thobari J, Satria CD, Handley A, Watts E, Cowley D, et al. Human neonatal rotavirus vaccine (RV3-BB) to target rotavirus from birth. N Engl J Med. 2018;378(8):719-30. [DOI:10.1056/NEJMoa1706804] [PMID] [PMCID]
10. Marsicovetere P, Ivatury SJ, White B, Holubar SD. Intestinal intussusception: etiology, diagnosis, and treatment. Clin Colon Rectal Surg. 2017;30(01):030-9. [DOI:10.1055/s-0036-1593429] [PMID] [PMCID]
11. Ananthakrishnan AN, Xavier RJ. Gastrointestinal diseases. Hunter's Tropical Medicine and Emerging Infectious Diseases: Elsevier; 2020. pp. 16-26. [DOI:10.1016/B978-0-323-55512-8.00003-X]
12. Hu Z-C, Tan Y-L, Huang S-G, Pan P, Liu X-B, Wang J, et al. Molecular imaging of Toll-like receptor 4 detects ischemia-reperfusion injury during intussusception. Oncotarget. 2017;9(8):7882. [DOI:10.18632/oncotarget.23609] [PMID] [PMCID]
13. Paul C, Anderson S. The Correlation Between Pediatric Intussusceptions and Celiac Disease. J Diagn Med Sonogr. 2019;35(5):419-24. [DOI:10.1177/8756479319855005]
14. Restivo V, Costantino C, Tramuto F, Vitale F. Hospitalization rates for intussusception in children aged 0-59 months from 2009 to 2014 in Italy. Hum Vaccin Immunother. 2017;13(2):445-9. [DOI:10.1080/21645515.2017.1264784] [PMID] [PMCID]
15. Acer-Demir T, Güney LH, Fakioğlu E, Gültekingil A. Comparison of clinical features of intussusception in terms of age and duration of symptoms. Pediatric Emergency Care. 2023;39(11):841-7. [DOI:10.1097/PEC.0000000000003061] [PMID]
16. Li Y, Zhou Q, Liu C, Sun C, Sun H, Li X, et al. Epidemiology, clinical characteristics, and treatment of children with acute intussusception: a case series. BMC Pediatrics. 2023;23(143):2-6. [DOI:10.1186/s12887-023-03961-y] [PMID] [PMCID]
17. Li XZ, Wang H, Song J, Liu Y, Lin YQ, Sun ZX. Ultrasonographic Diagnosis of Intussusception in Children: A Systematic Review and Meta‐Analysis. J Ultrasound Med. 2021;40(6):1077-84. [DOI:10.1002/jum.15504] [PMID]
18. Sun Z, Song G, Lian D, Zhang Q, Dong L. Process management of intussusception in children: a retrospective analysis in China. Pediatr Emerg Care. 2022;38(7):321-5. [DOI:10.1097/PEC.0000000000002700] [PMID] [PMCID]
19. Devine M, Coffey JC. Mesenteric Adenopathy and Adenitis. The Mesentery and Inflammation: Springer; 2023. pp. 127-48. [DOI:10.1007/978-3-031-17774-3_8]
20. Ehrenpreis ED. Mesenteric Adenitis. The Mesenteric Organ in Health and Disease. 2021. pp. 195-201. [DOI:10.1007/978-3-030-71963-0_22]
21. Karaseva O, Golikov D, Kharitonova AY, Gorelik A, Timofeeva A, Batunina I, et al. Intermittent intestinal intussusception in patients with mesenteric lymphadenitis in the ileocecal angle. Russ J Pediatr Surg. 2021;25(3):192-7. [DOI:10.18821/1560-9510-2021-25-3-192-197]
22. Shrestha A, Adhikari G. Childhood mesenteric adenitis-The spectrum of findings. Kathmandu Univ Med J. 2021;19(1):47-51. [DOI:10.3126/kumj.v20i1.49896] [DOI:10.3126/kumj.v19i1.49535]
23. Amuddhu SK, Chen Y, Nah SA. Inpatient admission versus emergency department management of intussusception in children: a systemic review and meta-analysis of outcomes. Eur J Pediatr Surg. 2019;29(01):007-13. [DOI:10.1055/s-0038-1668145] [PMID]
24. Rafei M. Diagnosis and treatment of intussusception in infants and children in Tabriz Children's Hospital from 2012 to 2017. J Tabriz Univ Med Sci. 2017;1(2):47.
25. Jo S, Lim IS, Chae SA, Yun SW, Lee NM, Kim SY, et al. Characteristics of intussusception among children in Korea: a nationwide epidemiological study. BMC Pediatrics. 2019;19:1-7. [DOI:10.1186/s12887-019-1592-6] [PMID] [PMCID]
26. Yan Q, Xu L, Chao J, Zhang Z, Wang H. Characteristics of intestinal-related lymphoid hyperplasia in children and its correlation with intussusception of children. BMC Pediatr. 2022;22(1):641. [DOI:10.1186/s12887-022-03675-7] [PMID] [PMCID]
27. Esteghamati A, Joulani M, Sayyahfar S, Salahi S, Babaie M, Shamshiri AR, et al. Incidence of intussusception in children less than five years of age: a pre-rotavirus vaccine survey from Iran, 2010-2015. Med J Islam Repub Iran. 2020;34:40. [DOI:10.47176/mjiri.34.40] [PMID] [PMCID]
28. Mpabalwani EM, Chitambala P, Chibumbya JN, Matapo B, Mutambo H, Mwenda JM, et al. Intussusception incidence rates in 9 Zambian hospitals, 2007-2011: prerotavirus vaccine introduction. Pediatr Infect Dis J. 2014;33:S94-S8. [DOI:10.1097/INF.0000000000000055] [PMID]
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
Copyright Policy
