Volume 8, Issue 33 (12-2000)                   J Adv Med Biomed Res 2000, 8(33): 4-11 | Back to browse issues page

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Heidarpour F, Rostami A, Derakhshandeh J, Sobhan A, Yousefi M. The Effects Of Different "Nacl" Concentrations In Drinkable Water Of Pregnant Rats On Their Newborns Blood Pressure (Bp) Of Maturation Period. J Adv Med Biomed Res 2000; 8 (33) :4-11
URL: http://journal.zums.ac.ir/article-1-720-en.html
Abstract:   (149192 Views)
Recently, in human communities, a relation between malnutrition before birth and hypertension, has been suggested. Patterns of malnutrition during embryonic period in rats, on the basis of measuring rat's Bp via tail caff, have provided decisive support for this theory.Electrolytes consumed by mother, in embryonic periods, also may change the homeostasis of the body fluids which genetically sensitize individuals during offspring.For studying the future effects of different concentrations of Nacl, variant amounts, Consists of 0.5, 1, 1.4, 1.6, 1.8 and 2 percent, were prepared and during the periods of pregnancy and lactation, these specific concentrations of salt in drinkable water, were offered to female rats.One group used distilled water and the other group, consumed drinkable water of Isfahan. All through the experience, rats nutrious diet, contained 2 percent of salt. After weaning, during the whole period of development, newborns of all groups utilized the above mentioned diet and drinkable water of Isfahan, as their consumed water. At the end of development period. 3 month rats of each group, were weighed Then mean systolic and dyastolic Bp of 20 rats from mothers which had consumed variant concentrations, were measured, directly.Mean systolic and dyastolic Bp of offspring which their mothers had used 0.5 and 1 percent concentrations, clearly showed a reduction, compared with those which their mothers had utilized more concentrated saline solutions, rats of above group, also had more weights.But Bp of rats from mothers which had used more concentrated saline solutions, showed an increase and they also had lower weights.
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Type of Study: Original Research Article |
Received: 2008/12/1 | Accepted: 2000/12/15 | Published: 2000/12/15

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