Volume 23, Issue 101 (8-2015)                   J Adv Med Biomed Res 2015, 23(101): 13-23 | Back to browse issues page

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Eghdam Zamiri R, Shokoufi S, Ghadimi Z, Baba Ali S S, Jafari S, Talebi Pour B, et al . The Differences in the Albumin, C-Reactive Protein and Platelet Levels in Patients with Gastric Diseases Admitted to Endoscopy Unit of Vali-e-Asr Hospital in Zanjan. J Adv Med Biomed Res 2015; 23 (101) :13-23
URL: http://journal.zums.ac.ir/article-1-3341-en.html
1- Dept. of Oncology, Vali-e-Asr Hospital, Zanjan University of Medical Sciences, Zanajn, Iran
2- Dept. of Internal Medicine, Vali-e-Asr Hospital, Zanjan University of Medical Sciences, Zanjan, Iran
3- Zanjan University of Medical Science, Zanjan, Iran
4- Dept. of Gastroenterology, Vali-e-Asr Hospital, Zanjan University of Medical Sciences, Zanajn, Iran
5- Vali-e-Asr Hospital, Zanjan University of Medical Sciences, Zanajn, Iran
6- Dept. of Oncology, Vali-e-Asr Hospital, Zanjan University of Medical Sciences, Zanajn, Iran , minoosh2000@yahoo.com
Abstract:   (160545 Views)

Background and Objective: Upper gastro intestinal cancers are considered to be a global health problem and gastric cancer is the fourth common malignancy worldwide. In cancer patients, low levels of albumin,
C-reactive protein and platelets are considered as bad prognostic factors. The objective of this study was to evaluate the levels of Albumin (Alb), C-reactive protein (CRP), and Platelets in patients admitted to Endoscopy Unit of Vali-e-Asr Hospital in Zanjan in 2011-2012.

Materials and Methods: 308 patients who had been admitted for upper gasterointestinal endoscopy to Endoscopy Unit of Vali-e-Asr Hospital in Zanjan were entered into this study. Through the upper endoscopy of all abnormal lesions went through biopsy and pathological studies were followed.

Results: Patients were assigned to three groups of normal, benign and malignant lesions and their platelets, albumin levels, BMI and C-reactive protein were measured and compared as prognostic factors. The mean BMI, in the malignant group was significantly lower than the other two groups) PV=0.051(. The mean values of serum albumin in the malignant group was significantly lower than the other two groups (PV=0.023). Meanwhile, the average level of CRP and platelets in the malignant group was significantly higher than the other two groups.  

Conclusion: Due to the high prevalence of gastrointestinal malignancies in Iran, measurement of albumin, C-reactive protein and platelet levels can be an efficient approach to diagnose or prognosis in these diseases.

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Type of Study: Clinical Trials |
Received: 2015/10/19 | Accepted: 2015/10/19 | Published: 2015/10/19

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