Volume 33, Issue 162 (Special Issue 2025)                   J Adv Med Biomed Res 2025, 33(162): 31-39 | Back to browse issues page

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Alyaseen F F. Assessment of Serum Calcium and Vitamin D in Autism Spectrum Disorders. J Adv Med Biomed Res 2025; 33 (162) :31-39
URL: http://journal.zums.ac.ir/article-1-7849-en.html
Assessment of Serum Calcium and Vitamin D in Autism Spectrum Disorders
Firas Fadhil Alyaseen *
Department of Pharmaceutical Sciences, College of Pharmacy, University of Thi-Qar, Thi-Qar, Iraq , firasalyaseen@utq.edu.iq
Abstract:   (174 Views)

Background & Objective: Autism is a neurodevelopmental disorder that affects social interaction, communication, and behavior. It is believed that biological and genetic factors play a key role in the development of autism. Children with autism spectrum disorder (ASD) often present with nutritional, metabolic, and gastrointestinal abnormalities that can affect their calcium and vitamin D3 states. The reason for assessing these parameters is based on biological, behavioral, and pharmacological factors that may increase the risk of disease abnormalities. This study aims to compare the autism patient group with a control group in terms of gender and age distribution, as well as assess the levels of calcium and Vitamin D3 in both groups.
 Materials & Methods: The study was conducted on 50 autism patients and 50 individuals in the control group. Data related to gender and age group were collected, along with measurements of calcium and Vitamin D3 levels in the blood. So, it was approved to conduct the study by the Thi-Qar Health Department, Research and Department of the College of Pharmacy / University of Thi-Qar. This study was conducted from 11/2024 to 4/2025, at Thi-Qar Rehabilitation Center for autistic disorders.
Results:  It showed significant differences between the two groups. The proportion of males in the autism group was higher (74%) compared to the control group (42%). This could be due to the normal variation of the selected samples in this study. The most represented age group in the autism patients was 7-10 years (42%), while the most represented age group in the control group was 11 years and older (50%). Additionally, the study found a significant decrease in both calcium and Vitamin D3 levels in autism patients compared to the control group.
Conclusion:  The findings suggest a significant relationship between calcium and Vitamin D3 deficiencies in autism patients, which may contribute to the severity of the symptoms.

Keywords: Serum Calcium, Vitamin D3, Children, Autism Spectrum Disorders
Full-Text [PDF 456 kb]   (16 Downloads)    
Type of Study: Original Research Article | Subject: Clinical Medicine
Received: 2025/09/29 | Accepted: 2025/11/12 | Published: 2025/12/29
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